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Photobac derived from bacteriochlorophyll-a shows potential for treating brain tumor in animal models by photodynamic therapy with desired pharmacokinetics and limited toxicity in rats and dogs.
Durrani FA, Cacaccio J, Turowski SG, Dukh M, Bshara W, Curtin L, Sexton S, Spernyak JA, Pandey RK. Durrani FA, et al. Among authors: turowski sg. Biomed Pharmacother. 2023 Dec;168:115731. doi: 10.1016/j.biopha.2023.115731. Epub 2023 Oct 17. Biomed Pharmacother. 2023. PMID: 37857248 Free PMC article.
Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium(III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging (MR, Fluorescence) and photodynamic therapy.
Spernyak JA, White WH 3rd, Ethirajan M, Patel NJ, Goswami L, Chen Y, Turowski S, Missert JR, Batt C, Mazurchuk R, Pandey RK. Spernyak JA, et al. Bioconjug Chem. 2010 May 19;21(5):828-35. doi: 10.1021/bc9005317. Bioconjug Chem. 2010. PMID: 20387862 Free PMC article.
Mechanisms of tumor vascular priming by a nanoparticulate doxorubicin formulation.
Roy Chaudhuri T, Arnold RD, Yang J, Turowski SG, Qu Y, Spernyak JA, Mazurchuk R, Mager DE, Straubinger RM. Roy Chaudhuri T, et al. Among authors: turowski sg. Pharm Res. 2012 Dec;29(12):3312-24. doi: 10.1007/s11095-012-0823-4. Epub 2012 Jul 14. Pharm Res. 2012. PMID: 22798260 Free PMC article.
Multifunctional Liposomes for Image-Guided Intratumoral Chemo-Phototherapy.
Miranda D, Carter K, Luo D, Shao S, Geng J, Li C, Chitgupi U, Turowski SG, Li N, Atilla-Gokcumen GE, Spernyak JA, Lovell JF. Miranda D, et al. Among authors: turowski sg. Adv Healthc Mater. 2017 Aug;6(16):10.1002/adhm.201700253. doi: 10.1002/adhm.201700253. Epub 2017 May 15. Adv Healthc Mater. 2017. PMID: 28504409 Free PMC article.
Irradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer.
Shafirstein G, Bellnier DA, Oakley E, Hamilton S, Habitzruther M, Tworek L, Hutson A, Spernyak JA, Sexton S, Curtin L, Turowski SG, Arshad H, Henderson B. Shafirstein G, et al. Among authors: turowski sg. Br J Cancer. 2018 Nov;119(10):1191-1199. doi: 10.1038/s41416-018-0210-y. Epub 2018 Oct 24. Br J Cancer. 2018. PMID: 30353043 Free PMC article.
25 results