Mrak P - Search Results

1

Generation of Bioactivity-Tailored FK506/FK520 Analogs by CRISPR Editing in Streptomyces tsukubaensis.

Buntin K, Mrak P, Pivk Lukančič P, Wollbrett S, Drčar T, Krastel P, Thibaut C, Salcius M, Gao X, Wang S, Weber E, Koplan E, Regenass H. Buntin K, et al. Among authors: mrak p. Chemistry. 2024 Jan 11;30(3):e202302350. doi: 10.1002/chem.202302350. Epub 2023 Nov 23. Chemistry. 2024. PMID: 37855054

2

Discovery of the actinoplanic acid pathway in Streptomyces rapamycinicus reveals a genetically conserved synergism with rapamycin.

Mrak P, Krastel P, Pivk Lukančič P, Tao J, Pistorius D, Moore CM. Mrak P, et al. J Biol Chem. 2018 Dec 28;293(52):19982-19995. doi: 10.1074/jbc.RA118.005314. Epub 2018 Oct 16. J Biol Chem. 2018. PMID: 30327433 Free PMC article.

3

Teleocidin-producing genotype of Streptomyces clavuligerus ATCC 27064.

Pivk Lukančič P, Drčar T, Bruccoleri R, Črnugelj M, Mrak P. Pivk Lukančič P, et al. Among authors: mrak p. Appl Microbiol Biotechnol. 2022 Feb;106(4):1521-1530. doi: 10.1007/s00253-022-11805-5. Epub 2022 Feb 9. Appl Microbiol Biotechnol. 2022. PMID: 35138454 Free PMC article.

4

FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis.

Goranovič D, Blažič M, Magdevska V, Horvat J, Kuščer E, Polak T, Santos-Aberturas J, Martínez-Castro M, Barreiro C, Mrak P, Kopitar G, Kosec G, Fujs S, Martín JF, Petković H. Goranovič D, et al. Among authors: mrak p. BMC Microbiol. 2012 Oct 19;12:238. doi: 10.1186/1471-2180-12-238. BMC Microbiol. 2012. PMID: 23083511 Free PMC article.

5

Origin of the allyl group in FK506 biosynthesis.

Goranovic D, Kosec G, Mrak P, Fujs S, Horvat J, Kuscer E, Kopitar G, Petkovic H. Goranovic D, et al. Among authors: mrak p. J Biol Chem. 2010 May 7;285(19):14292-300. doi: 10.1074/jbc.M109.059600. Epub 2010 Mar 1. J Biol Chem. 2010. PMID: 20194504 Free PMC article.

6

Oxytetracycline hyper-production through targeted genome reduction of Streptomyces rimosus.

Pšeničnik A, Slemc L, Avbelj M, Tome M, Šala M, Herron P, Shmatkov M, Petek M, Baebler Š, Mrak P, Hranueli D, Starčević A, Hunter IS, Petković H. Pšeničnik A, et al. Among authors: mrak p. mSystems. 2024 May 16;9(5):e0025024. doi: 10.1128/msystems.00250-24. Epub 2024 Apr 2. mSystems. 2024. PMID: 38564716 Free PMC article.

7

Novel chemobiosynthetic approach for exclusive production of FK506.

Kosec G, Goranovič D, Mrak P, Fujs S, Kuščer E, Horvat J, Kopitar G, Petković H. Kosec G, et al. Among authors: mrak p. Metab Eng. 2012 Jan;14(1):39-46. doi: 10.1016/j.ymben.2011.11.003. Epub 2011 Nov 12. Metab Eng. 2012. PMID: 22100790

8

Engineered, highly productive biosynthesis of artificial, lactonized statin side-chain building blocks: The hidden potential of Escherichia coli unleashed.

Vajdič T, Ošlaj M, Kopitar G, Mrak P. Vajdič T, et al. Among authors: mrak p. Metab Eng. 2014 Jul;24:160-72. doi: 10.1016/j.ymben.2014.05.012. Epub 2014 May 21. Metab Eng. 2014. PMID: 24858788 Free article.

9

A highly productive, whole-cell DERA chemoenzymatic process for production of key lactonized side-chain intermediates in statin synthesis.

Ošlaj M, Cluzeau J, Orkić D, Kopitar G, Mrak P, Casar Z. Ošlaj M, et al. Among authors: mrak p. PLoS One. 2013 May 7;8(5):e62250. doi: 10.1371/journal.pone.0062250. Print 2013. PLoS One. 2013. PMID: 23667462 Free PMC article.

10

Influence of archaeal lipids isolated from Aeropyrum pernix K1 on physicochemical properties of sphingomyelin-cholesterol liposomes.

Kejžar J, Mrak P, Osojnik Črnivec IG, Poklar Ulrih N. Kejžar J, et al. Among authors: mrak p. Biochim Biophys Acta Biomembr. 2024 Oct;1866(7):184374. doi: 10.1016/j.bbamem.2024.184374. Epub 2024 Jul 23. Biochim Biophys Acta Biomembr. 2024. PMID: 39053569 Free article.

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