Kong R - Search Results

1

Absorption, metabolism and excretion of ¹⁴C-emvododstat following repeat daily oral dose administration in human volunteers using a combination of microtracer radioactivity and high radioactivity doses.

Ma J, Laskin OL, Roffel AF, Vaes WHJ, Tang B, Kolnaar J, O'Keefe K, Golden L, Kong R. Ma J, et al. Among authors: kong r. Drug Metab Dispos. 2023 Oct 18;52(1):DMD-AR-2023-001471. doi: 10.1124/dmd.123.001471. Drug Metab Dispos. 2023. PMID: 37852795

2

Ataluren Pharmacokinetics in Healthy Japanese and Caucasian Subjects.

Kong R, Laskin OL, Kaushik D, Jin F, Ma J, McIntosh J, Souza M, Almstead N. Kong R, et al. Clin Pharmacol Drug Dev. 2019 Feb;8(2):172-178. doi: 10.1002/cpdd.645. Epub 2019 Jan 10. Clin Pharmacol Drug Dev. 2019. PMID: 30629861 Free PMC article. Clinical Trial.

3

Metabolism and Disposition of Ataluren after Oral Administration to Mice, Rats, Dogs, and Humans.

Kong R, Ma J, Hwang S, Goodwin E, Northcutt V, Babiak J, Almstead N, McIntosh J. Kong R, et al. Drug Metab Dispos. 2020 Apr;48(4):317-325. doi: 10.1124/dmd.119.089391. Epub 2020 Jan 24. Drug Metab Dispos. 2020. PMID: 31980502 Clinical Trial.

4

In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren.

Kong R, Ma J, Hwang S, Moon YC, Welch EM, Weetall M, Colacino JM, Almstead N, Babiak J, Goodwin E. Kong R, et al. Pharmacol Res Perspect. 2020 Apr;8(2):e00576. doi: 10.1002/prp2.576. Pharmacol Res Perspect. 2020. PMID: 32196986 Free PMC article.

5

LC-MS/MS quantification of ataluren and ataluren acyl glucuronide in human plasma/urine: application in clinical studies.

Kaushik D, Ma J, Gu G, Hwang S, Moon YC, Kong R. Kaushik D, et al. Among authors: kong r. Bioanalysis. 2020 Nov;12(21):1545-1555. doi: 10.4155/bio-2020-0214. Epub 2020 Oct 16. Bioanalysis. 2020. PMID: 33064028

6

Metabolite V, an epoxide species is a minor circulating metabolite in humans following a single oral dose of deflazacort.

Kong R, Ma J, Beers B, Kaushik D, Lin E, Goodwin E, Colacino J, Bibbiani F. Kong R, et al. Pharmacol Res Perspect. 2020 Dec;8(6):e00677. doi: 10.1002/prp2.677. Pharmacol Res Perspect. 2020. PMID: 33090712 Free PMC article.

7

The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.

Luban J, Sattler RA, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz SW. Luban J, et al. Among authors: kong r. Virus Res. 2021 Jan 15;292:198246. doi: 10.1016/j.virusres.2020.198246. Epub 2020 Nov 26. Virus Res. 2021. PMID: 33249060 Free PMC article.

8

Pharmacokinetics and Safety of PTC596, a Novel Tubulin-Binding Agent, in Subjects With Advanced Solid Tumors.

Shapiro GI, O'Mara E, Laskin OL, Gao L, Baird JD, Spiegel RJ, Kaushik D, Weetall M, Colacino J, O'Keefe K, Branstrom A, Goodwin E, Infante J, Bedard PL, Kong R. Shapiro GI, et al. Among authors: kong r. Clin Pharmacol Drug Dev. 2021 Aug;10(8):940-949. doi: 10.1002/cpdd.904. Epub 2021 Jan 13. Clin Pharmacol Drug Dev. 2021. PMID: 33440067 Clinical Trial.

9

In vitro cytochrome P450- and transporter-mediated drug interaction potential of 6β-hydroxy-21-desacetyl deflazacort-A major human metabolite of deflazacort.

Ma J, Beers B, Manohar R, Roe S, Colacino JM, Kong R. Ma J, et al. Among authors: kong r. Pharmacol Res Perspect. 2021 Apr;9(2):e00748. doi: 10.1002/prp2.748. Pharmacol Res Perspect. 2021. PMID: 33749127 Free PMC article.

10

Ataluren metabolism: Ataluren-O-1β-acyl glucuronide is a stable circulating metabolite in mouse, rat, dog and human.

Ma J, Risher N, Northcutt V, Moon YC, Weetall M, Welch E, Colacino J, Almstead N, Kong R. Ma J, et al. Among authors: kong r. Drug Metab Pharmacokinet. 2021 Jun;38:100393. doi: 10.1016/j.dmpk.2021.100393. Epub 2021 Mar 30. Drug Metab Pharmacokinet. 2021. PMID: 33872944 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

976 results

Search Page

Filters