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Absorption, metabolism and excretion of 14C-emvododstat following repeat daily oral dose administration in human volunteers using a combination of microtracer radioactivity and high radioactivity doses.
Ma J, Laskin OL, Roffel AF, Vaes WHJ, Tang B, Kolnaar J, O'Keefe K, Golden L, Kong R. Ma J, et al. Among authors: golden l. Drug Metab Dispos. 2023 Oct 18:DMD-AR-2023-001471. doi: 10.1124/dmd.123.001471. Online ahead of print. Drug Metab Dispos. 2023. PMID: 37852795 Free article.
First-in-Human Studies of Pharmacokinetics and Safety of Utreloxastat (PTC857), a Novel 15-Lipooxygenase Inhibitor for the Treatment of Amyotrophic Lateral Sclerosis.
Gao L, Giannousis P, Thoolen M, Kaushik D, Latham J, Tansy A, Ma J, Johnston M, Dali M, Golden L, Klein M, Kong R, Trimmer J. Gao L, et al. Among authors: golden l. Clin Pharmacol Drug Dev. 2023 Feb;12(2):141-151. doi: 10.1002/cpdd.1203. Epub 2022 Dec 14. Clin Pharmacol Drug Dev. 2023. PMID: 36516010 Free PMC article. Clinical Trial.
A clinical pharmacokinetic drug-drug interaction study between dextromethorphan and emvododstat, a potent anti-SARS-CoV-2 dihydroorotate dehydrogenase inhibitor.
Morton TL, Laskin OL, Kaushik D, Lee L, Ma J, Bar CM, Kristensen A, O'Keefe K, Golden L, Klein M, Kong R. Morton TL, et al. Among authors: golden l. Eur J Clin Pharmacol. 2023 Aug;79(8):1073-1080. doi: 10.1007/s00228-023-03513-4. Epub 2023 Jun 6. Eur J Clin Pharmacol. 2023. PMID: 37278823 Free PMC article.
Effect of External Beam Radiation Therapy and Brachytherapy on Circulating Myeloid-Derived Suppressor Cell Populations in Patients Treated Definitively for Cervical Cancer.
Wanhainen KM, Berkseth M, Sando N, Golden L, Techam A, Wieworka J, Bergerud KMB, Argenta P, O'Shea A, Erickson BK, Mullany S, Rivard C, Ghebre R, Teoh D, Reynolds M, Terezakis S, Yuan J, Sloan L. Wanhainen KM, et al. Among authors: golden l. Adv Radiat Oncol. 2024 Nov 14;10(2):101677. doi: 10.1016/j.adro.2024.101677. eCollection 2025 Feb. Adv Radiat Oncol. 2024. PMID: 39703718 Free PMC article.
Biophysical metabolic modeling of complex bacterial colony morphology.
Dukovski I, Golden L, Zhang J, Osborne M, Segrè D, Korolev KS. Dukovski I, et al. Among authors: golden l. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584915. doi: 10.1101/2024.03.13.584915. bioRxiv. 2024. PMID: 39502364 Free PMC article. Preprint.
153 results