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Page 1
A cell atlas foundation model for scalable search of similar human cells.
Heimberg G, Kuo T, DePianto DJ, Salem O, Heigl T, Diamant N, Scalia G, Biancalani T, Turley SJ, Rock JR, Corrada Bravo H, Kaminker J, Vander Heiden JA, Regev A. Heimberg G, et al. Among authors: turley sj. Nature. 2024 Nov 20. doi: 10.1038/s41586-024-08411-y. Online ahead of print. Nature. 2024. PMID: 39566551
IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines.
Sobral MC, Cabizzosu L, Kang SJ, Ruark K, Najibi AJ, Lane RS, Vitner E, Ijaz H, Dellacherie MO, Dacus MT, Tringides CM, Lázaro I, Pittet MJ, Müller S, Turley SJ, Mooney DJ. Sobral MC, et al. Among authors: turley sj. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2322356121. doi: 10.1073/pnas.2322356121. Epub 2024 Nov 18. Proc Natl Acad Sci U S A. 2024. PMID: 39556726
Systematic perturbation screens identify regulators of inflammatory macrophage states and a role for TNF mRNA m6A modification.
Haag SM, Xie S, Eidenschenk C, Fortin JP, Callow M, Costa M, Lun A, Cox C, Wu SZ, Pradhan RN, Lock J, Kuhn JA, Holokai L, Thai M, Freund E, Nissenbaum A, Keir M, Bohlen CJ, Martin S, Geiger-Schuller K, Hejase HA, Yaspan BL, Melo Carlos S, Turley SJ, Murthy A. Haag SM, et al. Among authors: turley sj. Nat Genet. 2024 Nov;56(11):2493-2505. doi: 10.1038/s41588-024-01962-w. Epub 2024 Oct 23. Nat Genet. 2024. PMID: 39443811
Durable lymph-node expansion is associated with the efficacy of therapeutic vaccination.
Najibi AJ, Lane RS, Sobral MC, Bovone G, Kang S, Freedman BR, Gutierrez Estupinan J, Elosegui-Artola A, Tringides CM, Dellacherie MO, Williams K, Ijaz H, Müller S, Turley SJ, Mooney DJ. Najibi AJ, et al. Among authors: turley sj. Nat Biomed Eng. 2024 Oct;8(10):1226-1242. doi: 10.1038/s41551-024-01209-3. Epub 2024 May 6. Nat Biomed Eng. 2024. PMID: 38710838 Free PMC article.
Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors.
Castiglioni A, Yang Y, Williams K, Gogineni A, Lane RS, Wang AW, Shyer JA, Zhang Z, Mittman S, Gutierrez A, Astarita JL, Thai M, Hung J, Yang YA, Pourmohamad T, Himmels P, De Simone M, Elstrott J, Capietto AH, Cubas R, Modrusan Z, Sandoval W, Ziai J, Gould SE, Fu W, Wang Y, Koerber JT, Sanjabi S, Mellman I, Turley SJ, Müller S. Castiglioni A, et al. Among authors: turley sj. Nat Commun. 2023 Aug 5;14(1):4703. doi: 10.1038/s41467-023-40398-4. Nat Commun. 2023. PMID: 37543621 Free PMC article.
In situ tumour arrays reveal early environmental control of cancer immunity.
Ortiz-Muñoz G, Brown M, Carbone CB, Pechuan-Jorge X, Rouilly V, Lindberg H, Ritter AT, Raghupathi G, Sun Q, Nicotra T, Mantri SR, Yang A, Doerr J, Nagarkar D, Darmanis S, Haley B, Mariathasan S, Wang Y, Gomez-Roca C, de Andrea CE, Spigel D, Wu T, Delamarre L, Schöneberg J, Modrusan Z, Price R, Turley SJ, Mellman I, Moussion C. Ortiz-Muñoz G, et al. Among authors: turley sj. Nature. 2023 Jun;618(7966):827-833. doi: 10.1038/s41586-023-06132-2. Epub 2023 May 31. Nature. 2023. PMID: 37258670 Free PMC article.
Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages.
D'Rozario J, Knoblich K, Lütge M, Shibayama CP, Cheng HW, Alexandre YO, Roberts D, Campos J, Dutton EE, Suliman M, Denton AE, Turley SJ, Boyd RL, Mueller SN, Ludewig B, Heng TSP, Fletcher AL. D'Rozario J, et al. Among authors: turley sj. Eur J Immunol. 2023 Sep;53(9):e2250355. doi: 10.1002/eji.202250355. Epub 2023 Jul 12. Eur J Immunol. 2023. PMID: 36991561 Free PMC article.
CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy.
Huseni MA, Wang L, Klementowicz JE, Yuen K, Breart B, Orr C, Liu LF, Li Y, Gupta V, Li C, Rishipathak D, Peng J, Şenbabaoǧlu Y, Modrusan Z, Keerthivasan S, Madireddi S, Chen YJ, Fraser EJ, Leng N, Hamidi H, Koeppen H, Ziai J, Hashimoto K, Fassò M, Williams P, McDermott DF, Rosenberg JE, Powles T, Emens LA, Hegde PS, Mellman I, Turley SJ, Wilson MS, Mariathasan S, Molinero L, Merchant M, West NR. Huseni MA, et al. Among authors: turley sj. Cell Rep Med. 2023 Jan 17;4(1):100878. doi: 10.1016/j.xcrm.2022.100878. Epub 2023 Jan 3. Cell Rep Med. 2023. PMID: 36599350 Free PMC article.
114 results