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Six-Month Outcomes from the Prospective, Multi-Center, Non-Randomized Clinical Study of the COVERA(™) Arterio VeNous (AV) Stent Graft in the Treatment of Stenosis in the VEnous OutfloW of AV Fistula Access Circuits (AVeNEW PAS).
Dolmatch B, Saber T, Underwood M; and AVeNEW PAS trial investigators. Dolmatch B, et al. Cardiovasc Intervent Radiol. 2025 Jan 9. doi: 10.1007/s00270-024-03930-7. Online ahead of print. Cardiovasc Intervent Radiol. 2025. PMID: 39789255
The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma.
Berardi A, Kaestner CL, Ghitti M, Quilici G, Cocomazzi P, Li J, Ballabio F, Zucchelli C, Knapp S, Licht JD, Musco G. Berardi A, et al. Among authors: licht jd. Nucleic Acids Res. 2025 Jan 7;53(1):gkae1121. doi: 10.1093/nar/gkae1121. Nucleic Acids Res. 2025. PMID: 39656918 Free PMC article.
Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs.
Saintilnord WN, Hegazy YA, Chesnutt K, Eckstein M, Cassidy RN, Dhahri H, Bennett RL, Melters DP, Lopes E, Fu Z, Lau K, Chandler DP, Poirier MG, Dalal Y, Licht JD, Fondufe-Mittendorf Y. Saintilnord WN, et al. Among authors: licht jd. bioRxiv [Preprint]. 2024 Nov 21:2024.11.18.624207. doi: 10.1101/2024.11.18.624207. bioRxiv. 2024. PMID: 39605447 Free PMC article. Preprint.
Genetic variation drives cancer cell adaptation to ECM stiffness.
Wang TC, Sawhney S, Morgan D, Bennett RL, Rashmi R, Estecio MR, Brock A, Singh I, Baer CF, Licht JD, Lele TP. Wang TC, et al. Among authors: licht jd. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2403062121. doi: 10.1073/pnas.2403062121. Epub 2024 Sep 20. Proc Natl Acad Sci U S A. 2024. PMID: 39302966 Free PMC article.
KDM6A regulates immune response genes in multiple myeloma.
Dupéré-Richer D, Riva A, Barwick BG, Maji S, Casellas Román H, Li J, De U, Sobh A, Quickstad G, Piper C, Kulis M, Ezponda T, Martín-Subero JI, Tonon G, Zhang W, Mitsiades CS, Boise LH, Bennett RL, Licht JD. Dupéré-Richer D, et al. Among authors: licht jd. Blood. 2024 Oct 3;144(14):1508-1520. doi: 10.1182/blood.2024024518. Blood. 2024. PMID: 39046770
Recruitment of FBXO22 for targeted degradation of NSD2.
Nie DY, Tabor JR, Li J, Kutera M, St-Germain J, Hanley RP, Wolf E, Paulakonis E, Kenney TMG, Duan S, Shrestha S, Owens DDG, Maitland MER, Pon A, Szewczyk M, Lamberto AJ, Menes M, Li F, Penn LZ, Barsyte-Lovejoy D, Brown NG, Barsotti AM, Stamford AW, Collins JL, Wilson DJ, Raught B, Licht JD, James LI, Arrowsmith CH. Nie DY, et al. Among authors: licht jd. Nat Chem Biol. 2024 Dec;20(12):1597-1607. doi: 10.1038/s41589-024-01660-y. Epub 2024 Jul 4. Nat Chem Biol. 2024. PMID: 38965384
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.
Sobh A, Encinas E, Patel A, Surapaneni G, Bonilla E, Kaestner C, Poullard J, Clerio M, Vasan K, Freeman T, Lv D, Dupéré-Richer D, Riva A, Barwick BG, Zhou D, Boise LH, Mitsiades CS, Kim B, Bennett RL, Chandel NS, Licht JD. Sobh A, et al. Among authors: licht jd. Blood. 2024 Jul 18;144(3):283-295. doi: 10.1182/blood.2023022859. Blood. 2024. PMID: 38598835
330 results