Sfeir A - Search Results

1

Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis.

Fu Y, Sacco O, DeBitetto E, Kanshin E, Ueberheide B, Sfeir A. Fu Y, et al. Among authors: sfeir a. Mol Cell. 2023 Oct 19;83(20):3740-3753.e9. doi: 10.1016/j.molcel.2023.09.026. Epub 2023 Oct 12. Mol Cell. 2023. PMID: 37832546 Free PMC article.

2

Stop pulling my strings - what telomeres taught us about the DNA damage response.

Lazzerini-Denchi E, Sfeir A. Lazzerini-Denchi E, et al. Among authors: sfeir a. Nat Rev Mol Cell Biol. 2016 Jun;17(6):364-78. doi: 10.1038/nrm.2016.43. Epub 2016 May 11. Nat Rev Mol Cell Biol. 2016. PMID: 27165790 Free PMC article. Review.

3

Safeguarding mitochondrial genomes in higher eukaryotes.

Fu Y, Tigano M, Sfeir A. Fu Y, et al. Among authors: sfeir a. Nat Struct Mol Biol. 2020 Aug;27(8):687-695. doi: 10.1038/s41594-020-0474-9. Epub 2020 Aug 6. Nat Struct Mol Biol. 2020. PMID: 32764737 Review.

4

Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance.

Tigano M, Vargas DC, Tremblay-Belzile S, Fu Y, Sfeir A. Tigano M, et al. Among authors: sfeir a. Nature. 2021 Mar;591(7850):477-481. doi: 10.1038/s41586-021-03269-w. Epub 2021 Feb 24. Nature. 2021. PMID: 33627873

5

Alternative splicing is a developmental switch for hTERT expression.

Penev A, Bazley A, Shen M, Boeke JD, Savage SA, Sfeir A. Penev A, et al. Among authors: sfeir a. Mol Cell. 2021 Jun 3;81(11):2349-2360.e6. doi: 10.1016/j.molcel.2021.03.033. Epub 2021 Apr 13. Mol Cell. 2021. PMID: 33852895 Free PMC article.

6

Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states.

Barry RM, Sacco O, Mameri A, Stojaspal M, Kartsonis W, Shah P, De Ioannes P, Hofr C, Côté J, Sfeir A. Barry RM, et al. Among authors: sfeir a. Genes Dev. 2022 Mar 1;36(5-6):313-330. doi: 10.1101/gad.349039.121. Epub 2022 Feb 24. Genes Dev. 2022. PMID: 35210222 Free PMC article.

7

RHINO directs MMEJ to repair DNA breaks in mitosis.

Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. Brambati A, et al. Among authors: sfeir a. Science. 2023 Aug 11;381(6658):653-660. doi: 10.1126/science.adh3694. Epub 2023 Jul 13. Science. 2023. PMID: 37440612 Free PMC article.

8

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

Sfeir A, Kosiyatrakul ST, Hockemeyer D, MacRae SL, Karlseder J, Schildkraut CL, de Lange T. Sfeir A, et al. Cell. 2009 Jul 10;138(1):90-103. doi: 10.1016/j.cell.2009.06.021. Cell. 2009. PMID: 19596237 Free PMC article.

9

Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis.

Pinzaru AM, Hom RA, Beal A, Phillips AF, Ni E, Cardozo T, Nair N, Choi J, Wuttke DS, Sfeir A, Denchi EL. Pinzaru AM, et al. Among authors: sfeir a. Cell Rep. 2016 Jun 7;15(10):2170-2184. doi: 10.1016/j.celrep.2016.05.008. Epub 2016 May 26. Cell Rep. 2016. PMID: 27239034 Free PMC article.

10

Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion.

Phillips AF, Millet AR, Tigano M, Dubois SM, Crimmins H, Babin L, Charpentier M, Piganeau M, Brunet E, Sfeir A. Phillips AF, et al. Among authors: sfeir a. Mol Cell. 2017 Feb 2;65(3):527-538.e6. doi: 10.1016/j.molcel.2016.12.014. Epub 2017 Jan 19. Mol Cell. 2017. PMID: 28111015 Free article.

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