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Page 1
Deep learning reveals diverging effects of altitude on aging.
Teklu AA, Heckenbach I, Petr MA, Bakula D, Keijzers G, Scheibye-Knudsen M. Teklu AA, et al. Among authors: heckenbach i. Geroscience. 2025 Jan 15. doi: 10.1007/s11357-024-01502-8. Online ahead of print. Geroscience. 2025. PMID: 39815037
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Norheim KL, Ben Ezra M, Heckenbach I, Andreasson LM, Eriksen LL, Dyhre-Petersen N, Damgaard MV, Berglind M, Pricolo L, Sampson D, Dellinger RW, Sverrild A, Treebak JT, Ditlev SB, Porsbjerg C, Scheibye-Knudsen M. Norheim KL, et al. Among authors: heckenbach i. Nat Aging. 2024 Dec;4(12):1772-1781. doi: 10.1038/s43587-024-00758-1. Epub 2024 Nov 15. Nat Aging. 2024. PMID: 39548320 Free PMC article. Clinical Trial.
CD38 regulates ovarian function and fecundity via NAD+ metabolism.
Perrone R, Ashok Kumaar PV, Haky L, Hahn C, Riley R, Balough J, Zaza G, Soygur B, Hung K, Prado L, Kasler HG, Tiwari R, Matsui H, Hormazabal GV, Heckenbach I, Scheibye-Knudsen M, Duncan FE, Verdin E. Perrone R, et al. Among authors: heckenbach i. iScience. 2023 Sep 16;26(10):107949. doi: 10.1016/j.isci.2023.107949. eCollection 2023 Oct 20. iScience. 2023. PMID: 37822499 Free PMC article.
Spatial mapping of cellular senescence: emerging challenges and opportunities.
Gurkar AU, Gerencser AA, Mora AL, Nelson AC, Zhang AR, Lagnado AB, Enninful A, Benz C, Furman D, Beaulieu D, Jurk D, Thompson EL, Wu F, Rodriguez F, Barthel G, Chen H, Phatnani H, Heckenbach I, Chuang JH, Horrell J, Petrescu J, Alder JK, Lee JH, Niedernhofer LJ, Kumar M, Königshoff M, Bueno M, Sokka M, Scheibye-Knudsen M, Neretti N, Eickelberg O, Adams PD, Hu Q, Zhu Q, Porritt RA, Dong R, Peters S, Victorelli S, Pengo T, Khaliullin T, Suryadevara V, Fu X, Bar-Joseph Z, Ji Z, Passos JF. Gurkar AU, et al. Among authors: heckenbach i. Nat Aging. 2023 Jul;3(7):776-790. doi: 10.1038/s43587-023-00446-6. Epub 2023 Jul 3. Nat Aging. 2023. PMID: 37400722 Free PMC article. Review.
Nuclear morphology is a deep learning biomarker of cellular senescence.
Heckenbach I, Mkrtchyan GV, Ezra MB, Bakula D, Madsen JS, Nielsen MH, Oró D, Osborne B, Covarrubias AJ, Idda ML, Gorospe M, Mortensen L, Verdin E, Westendorp R, Scheibye-Knudsen M. Heckenbach I, et al. Nat Aging. 2022 Aug;2(8):742-755. doi: 10.1038/s43587-022-00263-3. Epub 2022 Aug 15. Nat Aging. 2022. PMID: 37118134 Free PMC article.
Tracking the dynamics of cellular senescence.
Heckenbach I, Scheibye-Knudsen M. Heckenbach I, et al. Aging (Albany NY). 2023 Apr 17;15(9):3219-3220. doi: 10.18632/aging.204670. Epub 2023 Apr 17. Aging (Albany NY). 2023. PMID: 37071012 Free PMC article. No abstract available.
Histone malonylation is regulated by SIRT5 and KAT2A.
Zhang R, Bons J, Scheidemantle G, Liu X, Bielska O, Carrico C, Rose J, Heckenbach I, Scheibye-Knudsen M, Schilling B, Verdin E. Zhang R, et al. Among authors: heckenbach i. iScience. 2023 Feb 13;26(3):106193. doi: 10.1016/j.isci.2023.106193. eCollection 2023 Mar 17. iScience. 2023. PMID: 36879797 Free PMC article.
13 results