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Page 1
Design and testing of a humanized porcine donor for xenotransplantation.
Anand RP, Layer JV, Heja D, Hirose T, Lassiter G, Firl DJ, Paragas VB, Akkad A, Chhangawala S, Colvin RB, Ernst RJ, Esch N, Getchell K, Griffin AK, Guo X, Hall KC, Hamilton P, Kalekar LA, Kan Y, Karadagi A, Li F, Low SC, Matheson R, Nehring C, Otsuka R, Pandelakis M, Policastro RA, Pols R, Queiroz L, Rosales IA, Serkin WT, Stiede K, Tomosugi T, Xue Y, Zentner GE, Angeles-Albores D, Chris Chao J, Crabtree JN, Harken S, Hinkle N, Lemos T, Li M, Pantano L, Stevens D, Subedar OD, Tan X, Yin S, Anwar IJ, Aufhauser D, Capuano S, Kaufman DB, Knechtle SJ, Kwun J, Shanmuganayagam D, Markmann JF, Church GM, Curtis M, Kawai T, Youd ME, Qin W. Anand RP, et al. Among authors: church gm. Nature. 2023 Oct;622(7982):393-401. doi: 10.1038/s41586-023-06594-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821590 Free PMC article.
The whale shark genome reveals how genomic and physiological properties scale with body size.
Weber JA, Park SG, Luria V, Jeon S, Kim HM, Jeon Y, Bhak Y, Jun JH, Kim SW, Hong WH, Lee S, Cho YS, Karger A, Cain JW, Manica A, Kim S, Kim JH, Edwards JS, Bhak J, Church GM. Weber JA, et al. Among authors: church gm. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20662-20671. doi: 10.1073/pnas.1922576117. Epub 2020 Aug 4. Proc Natl Acad Sci U S A. 2020. PMID: 32753383 Free PMC article.
The inherent challenges of classifying senescence-Response.
Calimport SRG, Bentley BL, Stewart CE, Pawelec G, Scuteri A, Vinciguerra M, Slack C, Chen D, Harries LW, Marchant G, Fleming GA, Conboy M, Antebi A, Small GW, Gil J, Lakatta EG, Richardson A, Rosen C, Nikolich K, Wyss-Coray T, Steinman L, Montine T, de Magalhães JP, Campisi J, Church G. Calimport SRG, et al. Science. 2020 May 8;368(6491):595-596. doi: 10.1126/science.abb4073. Science. 2020. PMID: 32381713 Free PMC article. No abstract available.
Improved bacterial recombineering by parallelized protein discovery.
Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM. Wannier TM, et al. Among authors: church gm. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13689-13698. doi: 10.1073/pnas.2001588117. Epub 2020 May 28. Proc Natl Acad Sci U S A. 2020. PMID: 32467157 Free PMC article.
A Deep Learning Approach to Antibiotic Discovery.
Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Among authors: church gm. Cell. 2020 Apr 16;181(2):475-483. doi: 10.1016/j.cell.2020.04.001. Cell. 2020. PMID: 32302574 Free article. No abstract available.
New intranasal and injectable gene therapy for healthy life extension.
Jaijyan DK, Selariu A, Cruz-Cosme R, Tong M, Yang S, Stefa A, Kekich D, Sadoshima J, Herbig U, Tang Q, Church G, Parrish EL, Zhu H. Jaijyan DK, et al. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2121499119. doi: 10.1073/pnas.2121499119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537048 Free PMC article.
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.
Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Esvelt KM, et al. Among authors: church gm. Nat Methods. 2013 Nov;10(11):1116-21. doi: 10.1038/nmeth.2681. Epub 2013 Sep 29. Nat Methods. 2013. PMID: 24076762 Free PMC article.
Cas9 as a versatile tool for engineering biology.
Mali P, Esvelt KM, Church GM. Mali P, et al. Among authors: church gm. Nat Methods. 2013 Oct;10(10):957-63. doi: 10.1038/nmeth.2649. Nat Methods. 2013. PMID: 24076990 Free PMC article. Review.
Biocontainment of genetically modified organisms by synthetic protein design.
Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM. Mandell DJ, et al. Among authors: church gm. Nature. 2015 Feb 5;518(7537):55-60. doi: 10.1038/nature14121. Epub 2015 Jan 21. Nature. 2015. PMID: 25607366 Free PMC article.
Engineering and optimising deaminase fusions for genome editing.
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Yang L, et al. Nat Commun. 2016 Nov 2;7:13330. doi: 10.1038/ncomms13330. Nat Commun. 2016. PMID: 27804970 Free PMC article.
534 results