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A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Sprenger B, Moghadasi SA, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Kaserer T, Moro S, von Laer D, Heilmann E. Costacurta F, et al. Among authors: sauerwein a. bioRxiv [Preprint]. 2023 Oct 4:2023.09.22.558628. doi: 10.1101/2023.09.22.558628. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Sep 11;20(9):e1012522. doi: 10.1371/journal.ppat.1012522 PMID: 37808638 Free PMC article. Updated. Preprint.
Study of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir.
Krismer L, Schöppe H, Rauch S, Bante D, Sprenger B, Naschberger A, Costacurta F, Fürst A, Sauerwein A, Rupp B, Kaserer T, von Laer D, Heilmann E. Krismer L, et al. Among authors: sauerwein a. Npj Viruses. 2024;2(1):23. doi: 10.1038/s44298-024-00028-2. Epub 2024 Jun 24. Npj Viruses. 2024. PMID: 38933182 Free PMC article.
Highly specific SARS-CoV-2 main protease (Mpro) mutations against the clinical antiviral ensitrelvir selected in a safe, VSV-based system.
Rauch S, Costacurta F, Schöppe H, Peng JY, Bante D, Erisoez EE, Sprenger B, He X, Moghadasi SA, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Wang D, Naschberger A, Dunzendorfer-Matt T, Kaserer T, von Laer D, Heilmann E. Rauch S, et al. Among authors: sauerwein a. Antiviral Res. 2024 Nov;231:105969. doi: 10.1016/j.antiviral.2024.105969. Epub 2024 Jul 23. Antiviral Res. 2024. PMID: 39053514 Free article.
A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Peng JY, Sprenger B, He X, Moghadasi SA, Egger LM, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Dunzendorfer-Matt T, Naschberger A, Wang D, Kaserer T, Moro S, von Laer D, Heilmann E. Costacurta F, et al. Among authors: sauerwein a. PLoS Pathog. 2024 Sep 11;20(9):e1012522. doi: 10.1371/journal.ppat.1012522. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39259728 Free PMC article.
Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2.
Soloviev Z, Bullock JMA, James JMB, Sauerwein AC, Nettleship JE, Owens RJ, Hansen DF, Topf M, Thalassinos K. Soloviev Z, et al. Among authors: sauerwein ac. Biochim Biophys Acta Proteins Proteom. 2022 Mar 1;1870(3):140759. doi: 10.1016/j.bbapap.2022.140759. Epub 2022 Jan 18. Biochim Biophys Acta Proteins Proteom. 2022. PMID: 35051665 Free PMC article.
Supercycled homonuclear dipolar decoupling sequences in solid-state NMR.
Paul S, Thakur RS, Goswami M, Sauerwein AC, Mamone S, Concistrè M, Förster H, Levitt MH, Madhu PK. Paul S, et al. Among authors: sauerwein ac. J Magn Reson. 2009 Mar;197(1):14-9. doi: 10.1016/j.jmr.2008.11.011. Epub 2008 Nov 27. J Magn Reson. 2009. PMID: 19091609
11 results