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An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1.
Deng H, Ge H, Dubey C, Losmanova T, Medová M, Konstantinidou G, Mutlu SM, Birrer FE, Brodie TM, Stroka D, Wang W, Peng RW, Dorn P, Marti TM. Deng H, et al. Among authors: dorn p. Cancer Immunol Immunother. 2023 Dec;72(12):4457-4470. doi: 10.1007/s00262-023-03542-z. Epub 2023 Oct 5. Cancer Immunol Immunother. 2023. PMID: 37796299 Free PMC article.
Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model.
Bichsel CA, Wang L, Froment L, Berezowska S, Müller S, Dorn P, Marti TM, Peng RW, Geiser T, Schmid RA, Guenat OT, Hall SRR. Bichsel CA, et al. Among authors: dorn p. Sci Rep. 2017 Sep 6;7(1):10636. doi: 10.1038/s41598-017-09928-1. Sci Rep. 2017. PMID: 28878242 Free PMC article.
Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549.
Tièche CC, Gao Y, Bührer ED, Hobi N, Berezowska SA, Wyler K, Froment L, Weis S, Peng RW, Bruggmann R, Schär P, Amrein MA, Hall SRR, Dorn P, Kocher G, Riether C, Ochsenbein A, Schmid RA, Marti TM. Tièche CC, et al. Among authors: dorn p. Neoplasia. 2019 Feb;21(2):185-196. doi: 10.1016/j.neo.2018.09.008. Epub 2018 Dec 27. Neoplasia. 2019. PMID: 30591423 Free PMC article.
CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung.
Wang L, Dorn P, Zeinali S, Froment L, Berezowska S, Kocher GJ, Alves MP, Brügger M, Esteves BIO, Blank F, Wotzkow C, Steiner S, Amacker M, Peng RW, Marti TM, Guenat OT, Bode PK, Moehrlen U, Schmid RA, Hall SRR. Wang L, et al. Among authors: dorn p. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L813-L830. doi: 10.1152/ajplung.00146.2019. Epub 2020 Feb 19. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32073879 Free article.
EpCAM+CD73+ mark epithelial progenitor cells in postnatal human lung and are associated with pathogenesis of pulmonary disease including lung adenocarcinoma.
Wang L, Dorn P, Simillion C, Froment L, Berezowska S, Tschanz SA, Haenni B, Blank F, Wotzkow C, Peng RW, Marti TM, Bode PK, Moehrlen U, Schmid RA, Hall SRR. Wang L, et al. Among authors: dorn p. Am J Physiol Lung Cell Mol Physiol. 2020 Nov 1;319(5):L794-L809. doi: 10.1152/ajplung.00279.2019. Epub 2020 Jul 29. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32726135 Free article.
210 results