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Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice.
Chen SY, Beretta M, Olzomer EM, Alexopoulos SJ, Shah DP, Byrne FL, Salamoun JM, Garcia CJ, Smith GC, Larance M, Philp A, Turner N, Santos WL, Cantley J, Hoehn KL. Chen SY, et al. Among authors: cantley j. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166908. doi: 10.1016/j.bbadis.2023.166908. Epub 2023 Oct 2. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 37793464 Free PMC article.
High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice.
Burchfield JG, Kebede MA, Meoli CC, Stöckli J, Whitworth PT, Wright AL, Hoffman NJ, Minard AY, Ma X, Krycer JR, Nelson ME, Tan SX, Yau B, Thomas KC, Wee NKY, Khor EC, Enriquez RF, Vissel B, Biden TJ, Baldock PA, Hoehn KL, Cantley J, Cooney GJ, James DE, Fazakerley DJ. Burchfield JG, et al. Among authors: cantley j. J Biol Chem. 2018 Apr 13;293(15):5731-5745. doi: 10.1074/jbc.RA117.000808. Epub 2018 Feb 13. J Biol Chem. 2018. PMID: 29440390 Free PMC article.
Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion.
Veprik A, Denwood G, Liu D, Bany Bakar R, Morfin V, McHugh K, Tebeka NN, Vetterli L, Yonova-Doing E, Gribble F, Reimann F, Hoehn KL, Hemsley PA, Ahnfelt-Rønne J, Rorsman P, Zhang Q, de Wet H, Cantley J. Veprik A, et al. Among authors: cantley j. Commun Biol. 2022 Mar 18;5(1):238. doi: 10.1038/s42003-022-03170-w. Commun Biol. 2022. PMID: 35304577 Free PMC article.
Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice.
Chen SY, Beretta M, Olzomer EM, Shah DP, Wong DYH, Alexopoulos SJ, Aleksovska I, Salamoun JM, Garcia CJ, Cochran BJ, Rye KA, Smith GC, Byrne FL, Morris MJ, Santos WL, Cantley J, Hoehn KL. Chen SY, et al. Among authors: cantley j. Mol Metab. 2023 Mar;69:101684. doi: 10.1016/j.molmet.2023.101684. Epub 2023 Jan 31. Mol Metab. 2023. PMID: 36731653 Free PMC article.
Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation.
Sue N, Thai LM, Saito A, Boyer CK, Fordham AM, Yan C, Davenport A, Tao J, Bensellam M, Cantley J, Shi YC, Stephens SB, Imaizumi K, Biden TJ. Sue N, et al. Among authors: cantley j. Mol Metab. 2024 Jan;79:101845. doi: 10.1016/j.molmet.2023.101845. Epub 2023 Nov 25. Mol Metab. 2024. PMID: 38013154 Free PMC article.
74 results