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In search of novel highly active mitochondria-targeted antioxidants: thymoquinone and its cationic derivatives.
Severina II, Severin FF, Korshunova GA, Sumbatyan NV, Ilyasova TM, Simonyan RA, Rogov AG, Trendeleva TA, Zvyagilskaya RA, Dugina VB, Domnina LV, Fetisova EK, Lyamzaev KG, Vyssokikh MY, Chernyak BV, Skulachev MV, Skulachev VP, Sadovnichii VA. Severina II, et al. Among authors: rogov ag. FEBS Lett. 2013 Jun 27;587(13):2018-24. doi: 10.1016/j.febslet.2013.04.043. Epub 2013 May 10. FEBS Lett. 2013. PMID: 23665033 Free article. Review.
Mitochondria-targeted 1,4-naphthoquinone (SkQN) is a powerful prooxidant and cytotoxic agent.
Goleva TN, Lyamzaev KG, Rogov AG, Khailova LS, Epremyan KK, Shumakovich GP, Domnina LV, Ivanova OY, Marmiy NV, Zinevich TV, Esipov DS, Zvyagilskaya RA, Skulachev VP, Chernyak BV. Goleva TN, et al. Among authors: rogov ag. Biochim Biophys Acta Bioenerg. 2020 Aug 1;1861(8):148210. doi: 10.1016/j.bbabio.2020.148210. Epub 2020 Apr 17. Biochim Biophys Acta Bioenerg. 2020. PMID: 32305410 Free article.
SkQThy, a novel and promising mitochondria-targeted antioxidant.
Goleva TN, Rogov AG, Korshunova GA, Trendeleva TA, Mamaev DV, Aliverdieva DA, Zvyagilskaya RA. Goleva TN, et al. Among authors: rogov ag. Mitochondrion. 2019 Nov;49:206-216. doi: 10.1016/j.mito.2019.09.001. Epub 2019 Sep 6. Mitochondrion. 2019. PMID: 31499216
21 results