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Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo.
Nilsen KE, Zhang B, Skjesol A, Ryan L, Vagle H, Bøe MH, Orning P, Kim H, Bakke SS, Elamurugan K, Mestvedt IB, Stenvik J, Husebye H, Lien E, Espevik T, Yurchenko M. Nilsen KE, et al. Among authors: espevik t. Life Sci Alliance. 2023 Oct 3;6(12):e202302164. doi: 10.26508/lsa.202302164. Print 2023 Dec. Life Sci Alliance. 2023. PMID: 37788908 Free PMC article.
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice.
Olsen MB, Kong XY, Louwe MC, Lauritzen KH, Schanke Y, Kaasbøll OJ, Attramadal H, Øgaard J, Holm S, Aukrust P, Ryan L, Espevik T, Yurchenko M, Halvorsen B. Olsen MB, et al. Among authors: espevik t. Front Immunol. 2024 Apr 15;15:1383505. doi: 10.3389/fimmu.2024.1383505. eCollection 2024. Front Immunol. 2024. PMID: 38686379 Free PMC article.
Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance.
Zhang B, Orning P, Lehman JW, Dinis A, Torres-Ulloa L, Elling R, Kelliher MA, Bertin J, Proulx MK, Ryan L, Kandasamy R, Espevik T, Pai AA, Fitzgerald KA, Lien E. Zhang B, et al. Among authors: espevik t. bioRxiv [Preprint]. 2024 Nov 29:2024.11.27.625707. doi: 10.1101/2024.11.27.625707. bioRxiv. 2024. PMID: 39651143 Free PMC article. Preprint.
The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation.
Fageräng B, Cyranka L, Schjalm C, McAdam KE, Larsen CS, Heinzelbecker J, Gedde-Dahl T, Würzner R, Espevik T, Tjønnfjord GE, Garred P, Barratt-Due A, Tvedt THA, Mollnes TE. Fageräng B, et al. Among authors: espevik t. Front Immunol. 2024 Jun 13;15:1422370. doi: 10.3389/fimmu.2024.1422370. eCollection 2024. Front Immunol. 2024. PMID: 38938578 Free PMC article.
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM, Pryor M, Yang ZH, Remaley AT, Mollnes TE, Hewitt SM, Yan B, Kazemian M, Kiss MG, Binder CJ, Halvorsen B, Espevik T, Kemper C. Niyonzima N, et al. Among authors: espevik t. Sci Immunol. 2021 Dec 24;6(66):eabf2489. doi: 10.1126/sciimmunol.abf2489. Epub 2021 Dec 24. Sci Immunol. 2021. PMID: 34932384 Free PMC article.
301 results