Shlomchik MJ - Search Results

1

B cell-intrinsic Myd88 regulates disease progression in murine lupus.

Tilstra JS, Kim M, Gordon RA, Leibler C, Cosgrove HA, Bastacky S, Nickerson KM, Shlomchik MJ. Tilstra JS, et al. Among authors: shlomchik mj. J Exp Med. 2023 Dec 4;220(12):e20230263. doi: 10.1084/jem.20230263. Epub 2023 Oct 3. J Exp Med. 2023. PMID: 37787782 Free PMC article.

2

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ. Christensen SR, et al. Among authors: shlomchik mj. Immunity. 2006 Sep;25(3):417-28. doi: 10.1016/j.immuni.2006.07.013. Immunity. 2006. PMID: 16973389 Free article.

3

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus.

Nickerson KM, Christensen SR, Shupe J, Kashgarian M, Kim D, Elkon K, Shlomchik MJ. Nickerson KM, et al. Among authors: shlomchik mj. J Immunol. 2010 Feb 15;184(4):1840-8. doi: 10.4049/jimmunol.0902592. Epub 2010 Jan 20. J Immunol. 2010. PMID: 20089701 Free PMC article.

4

TLR9 promotes tolerance by restricting survival of anergic anti-DNA B cells, yet is also required for their activation.

Nickerson KM, Christensen SR, Cullen JL, Meng W, Luning Prak ET, Shlomchik MJ. Nickerson KM, et al. Among authors: shlomchik mj. J Immunol. 2013 Feb 15;190(4):1447-56. doi: 10.4049/jimmunol.1202115. Epub 2013 Jan 7. J Immunol. 2013. PMID: 23296704 Free PMC article.

5

Exacerbated autoimmunity in the absence of TLR9 in MRL.Fas(lpr) mice depends on Ifnar1.

Nickerson KM, Cullen JL, Kashgarian M, Shlomchik MJ. Nickerson KM, et al. Among authors: shlomchik mj. J Immunol. 2013 Apr 15;190(8):3889-94. doi: 10.4049/jimmunol.1203525. Epub 2013 Mar 6. J Immunol. 2013. PMID: 23467932 Free PMC article.

6

Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.

Getahun A, Beavers NA, Larson SR, Shlomchik MJ, Cambier JC. Getahun A, et al. Among authors: shlomchik mj. J Exp Med. 2016 May 2;213(5):751-69. doi: 10.1084/jem.20150537. Epub 2016 Apr 25. J Exp Med. 2016. PMID: 27114609 Free PMC article.

7

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice.

Nickerson KM, Wang Y, Bastacky S, Shlomchik MJ. Nickerson KM, et al. Among authors: shlomchik mj. PLoS One. 2017 Mar 9;12(3):e0173471. doi: 10.1371/journal.pone.0173471. eCollection 2017. PLoS One. 2017. PMID: 28278279 Free PMC article.

8

Lupus and proliferative nephritis are PAD4 independent in murine models.

Gordon RA, Herter JM, Rosetti F, Campbell AM, Nishi H, Kashgarian M, Bastacky SI, Marinov A, Nickerson KM, Mayadas TN, Shlomchik MJ. Gordon RA, et al. Among authors: shlomchik mj. JCI Insight. 2017 May 18;2(10):e92926. doi: 10.1172/jci.insight.92926. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515361 Free PMC article.

9

B Cell-Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B Cell Immune Responses.

Sweet RA, Nickerson KM, Cullen JL, Wang Y, Shlomchik MJ. Sweet RA, et al. Among authors: shlomchik mj. J Immunol. 2017 Aug 1;199(3):885-893. doi: 10.4049/jimmunol.1600861. Epub 2017 Jun 28. J Immunol. 2017. PMID: 28659358 Free PMC article.

10

Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted.

Tilstra JS, Avery L, Menk AV, Gordon RA, Smita S, Kane LP, Chikina M, Delgoffe GM, Shlomchik MJ. Tilstra JS, et al. Among authors: shlomchik mj. J Clin Invest. 2018 Nov 1;128(11):4884-4897. doi: 10.1172/JCI120859. Epub 2018 Sep 24. J Clin Invest. 2018. PMID: 30130253 Free PMC article.

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