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Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.
Medica S, Crawford LB, Denton M, Min CK, Jones TA, Alexander T, Parkins CJ, Diggins NL, Streblow GJ, Mayo AT, Kreklywich CN, Smith P, Jeng S, McWeeney S, Hancock MH, Yurochko A, Cohen MS, Caposio P, Streblow DN. Medica S, et al. Among authors: smith p. PLoS Pathog. 2023 Oct 2;19(10):e1011682. doi: 10.1371/journal.ppat.1011682. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37782657 Free PMC article.
Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes.
Pal P, Fox JM, Hawman DW, Huang YJ, Messaoudi I, Kreklywich C, Denton M, Legasse AW, Smith PP, Johnson S, Axthelm MK, Vanlandingham DL, Streblow DN, Higgs S, Morrison TE, Diamond MS. Pal P, et al. Among authors: smith pp. J Virol. 2014 Aug;88(15):8213-26. doi: 10.1128/JVI.01032-14. Epub 2014 May 14. J Virol. 2014. PMID: 24829346 Free PMC article.
Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.
Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, DeFilippis VR, Denton M, Smith PP, Messer WB, Colgin LM, Ducore RM, Grigsby PL, Hennebold JD, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Wiley CA, Nelson JA, Streblow DN. Hirsch AJ, et al. Among authors: smith pp, smith jl. PLoS Pathog. 2017 Mar 9;13(3):e1006219. doi: 10.1371/journal.ppat.1006219. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28278237 Free PMC article.
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