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Page 1
Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates.
Stuible M, Schrag JD, Sheff J, Zoubchenok D, Lord-Dufour S, Cass B, L'Abbé D, Pelletier A, Rossotti MA, Tanha J, Gervais C, Maurice R, El Bakkouri M, Acchione M, Durocher Y. Stuible M, et al. Among authors: sheff j. Sci Rep. 2023 Oct 1;13(1):16498. doi: 10.1038/s41598-023-43661-2. Sci Rep. 2023. PMID: 37779126 Free PMC article.
Binding symmetry and surface flexibility mediate antibody self-association.
Schrag JD, Picard MÈ, Gaudreault F, Gagnon LP, Baardsnes J, Manenda MS, Sheff J, Deprez C, Baptista C, Hogues H, Kelly JF, Purisima EO, Shi R, Sulea T. Schrag JD, et al. Among authors: sheff j. MAbs. 2019 Oct;11(7):1300-1318. doi: 10.1080/19420862.2019.1632114. Epub 2019 Jul 18. MAbs. 2019. PMID: 31318308 Free PMC article.
Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX.
Sheff JG, Kelly JF, Robotham A, Sulea T, Malenfant F, L'Abbé D, Duchesne M, Pelletier A, Lefebvre J, Acel A, Parat M, Gosselin M, Wu C, Fortin Y, Baardsnes J, Van Faassen H, Awrey S, Chafe SC, McDonald PC, Dedhar S, Lenferink AEG. Sheff JG, et al. MAbs. 2021 Jan-Dec;13(1):1997072. doi: 10.1080/19420862.2021.1997072. MAbs. 2021. PMID: 34812124 Free PMC article.
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models.
Rossotti MA, van Faassen H, Tran AT, Sheff J, Sandhu JK, Duque D, Hewitt M, Wen X, Bavananthasivam J, Beitari S, Matte K, Laroche G, Giguère PM, Gervais C, Stuible M, Guimond J, Perret S, Hussack G, Langlois MA, Durocher Y, Tanha J. Rossotti MA, et al. Among authors: sheff j. Commun Biol. 2022 Sep 9;5(1):933. doi: 10.1038/s42003-022-03866-z. Commun Biol. 2022. PMID: 36085335 Free PMC article.
A Novel Antigen Design Strategy to Isolate Single-Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models.
Martina M, Banderali U, Yogi A, Arbabi Ghahroudi M, Liu H, Sulea T, Durocher Y, Hussack G, van Faassen H, Chakravarty B, Liu QY, Iqbal U, Ling B, Lessard E, Sheff J, Robotham A, Callaghan D, Moreno M, Comas T, Ly D, Stanimirovic D. Martina M, et al. Among authors: sheff j. Adv Sci (Weinh). 2024 Oct;11(40):e2405432. doi: 10.1002/advs.202405432. Epub 2024 Aug 29. Adv Sci (Weinh). 2024. PMID: 39206821 Free PMC article.
22 results