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Page 1
Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Chi G, Dietz L, Tang H, Snee M, Scacioc A, Wang D, Mckinley G, Mukhopadhyay SMM, Pike ACW, Chalk R, Burgess-Brown NA, Timmermans JP, van Putte W, Robinson CV, Dürr KL. Chi G, et al. Among authors: durr kl. Sci Adv. 2023 Sep 29;9(39):eadg8229. doi: 10.1126/sciadv.adg8229. Epub 2023 Sep 29. Sci Adv. 2023. PMID: 37774028 Free PMC article.
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
Chi G, Ebenhoch R, Man H, Tang H, Tremblay LE, Reggiano G, Qiu X, Bohstedt T, Liko I, Almeida FG, Garneau AP, Wang D, McKinley G, Moreau CP, Bountra KD, Abrusci P, Mukhopadhyay SMM, Fernandez-Cid A, Slimani S, Lavoie JL, Burgess-Brown NA, Tehan B, DiMaio F, Jazayeri A, Isenring P, Robinson CV, Dürr KL. Chi G, et al. Among authors: durr kl. EMBO J. 2021 Jul 15;40(14):e107294. doi: 10.15252/embj.2020107294. Epub 2021 May 25. EMBO J. 2021. PMID: 34031912 Free PMC article.
Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain.
Chi G, Liang Q, Sridhar A, Cowgill JB, Sader K, Radjainia M, Qian P, Castro-Hartmann P, Venkaya S, Singh NK, McKinley G, Fernandez-Cid A, Mukhopadhyay SMM, Burgess-Brown NA, Delemotte L, Covarrubias M, Dürr KL. Chi G, et al. Among authors: durr kl. Nat Commun. 2022 Jul 15;13(1):4087. doi: 10.1038/s41467-022-29594-w. Nat Commun. 2022. PMID: 35840580 Free PMC article.
Expression Screening of Human Integral Membrane Proteins Using BacMam.
Mahajan P, Ellis K, Mukhopadhyay S, Fernandez-Cid A, Chi G, Man H, Dürr KL, Burgess-Brown NA. Mahajan P, et al. Among authors: durr kl. Methods Mol Biol. 2021;2199:95-115. doi: 10.1007/978-1-0716-0892-0_6. Methods Mol Biol. 2021. PMID: 33125646
The RESOLUTE consortium: unlocking SLC transporters for drug discovery.
Superti-Furga G, Lackner D, Wiedmer T, Ingles-Prieto A, Barbosa B, Girardi E, Goldmann U, Gürtl B, Klavins K, Klimek C, Lindinger S, Liñeiro-Retes E, Müller AC, Onstein S, Redinger G, Reil D, Sedlyarov V, Wolf G, Crawford M, Everley R, Hepworth D, Liu S, Noell S, Piotrowski M, Stanton R, Zhang H, Corallino S, Faedo A, Insidioso M, Maresca G, Redaelli L, Sassone F, Scarabottolo L, Stucchi M, Tarroni P, Tremolada S, Batoulis H, Becker A, Bender E, Chang YN, Ehrmann A, Müller-Fahrnow A, Pütter V, Zindel D, Hamilton B, Lenter M, Santacruz D, Viollet C, Whitehurst C, Johnsson K, Leippe P, Baumgarten B, Chang L, Ibig Y, Pfeifer M, Reinhardt J, Schönbett J, Selzer P, Seuwen K, Bettembourg C, Biton B, Czech J, de Foucauld H, Didier M, Licher T, Mikol V, Pommereau A, Puech F, Yaligara V, Edwards A, Bongers BJ, Heitman LH, IJzerman AP, Sijben HJ, van Westen GJP, Grixti J, Kell DB, Mughal F, Swainston N, Wright-Muelas M, Bohstedt T, Burgess-Brown N, Carpenter L, Dürr K, Hansen J, Scacioc A, Banci G, Colas C, Digles D, Ecker G, Füzi B, Gamsjäger V, Grandits M, Martini R, Troger F, Altermatt P, Doucerain C, Dürrenberger F, Manolova V, Steck AL, Sundström H, Wilhelm M, Steppan CM. Superti-Furga G, et al. Nat Rev Drug Discov. 2020 Jul;19(7):429-430. doi: 10.1038/d41573-020-00056-6. Nat Rev Drug Discov. 2020. PMID: 32265506 No abstract available.
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2.
Li HZ, Pike ACW, Chang YN, Prakaash D, Gelova Z, Stanka J, Moreau C, Scott HC, Wunder F, Wolf G, Scacioc A, McKinley G, Batoulis H, Mukhopadhyay S, Garofoli A, Pinto-Fernández A, Kessler BM, Burgess-Brown NA, Štefanić S, Wiedmer T, Dürr KL, Puetter V, Ehrmann A, Khalid S, Ingles-Prieto A, Superti-Furga G, Sauer DB. Li HZ, et al. Among authors: durr kl. Nat Commun. 2025 Jan 16;16(1):721. doi: 10.1038/s41467-025-55942-7. Nat Commun. 2025. PMID: 39820269 Free PMC article.
Protein Binder Toolbox for Studies of Solute Carrier Transporters.
Gelová Z, Ingles-Prieto A, Bohstedt T, Frommelt F, Chi G, Chang YN, Garcia J, Wolf G, Azzollini L, Tremolada S, Scacioc A, Hansen JS, Serrano I, Droce A, Bernal JC, Burgess-Brown NA, Carpenter EP, Dürr KL, Kristensen P, Geertsma ER, Štefanić S, Scarabottolo L, Wiedmer T, Puetter V, Sauer DB, Superti-Furga G. Gelová Z, et al. Among authors: durr kl. J Mol Biol. 2024 Aug 15;436(16):168665. doi: 10.1016/j.jmb.2024.168665. Epub 2024 Jun 13. J Mol Biol. 2024. PMID: 38878854
25 results