Sansom MSP - Search Results

1

Structure of the native chemotaxis core signaling unit from phage E-protein lysed E. coli cells.

Cassidy CK, Qin Z, Frosio T, Gosink K, Yang Z, Sansom MSP, Stansfeld PJ, Parkinson JS, Zhang P. Cassidy CK, et al. Among authors: sansom msp. mBio. 2023 Oct 31;14(5):e0079323. doi: 10.1128/mbio.00793-23. Epub 2023 Sep 29. mBio. 2023. PMID: 37772839 Free PMC article.

2

Rocking the MBOAT: Structural insights into the membrane bound O-acyltransferase family.

Coupland CE, Ansell TB, Sansom MSP, Siebold C. Coupland CE, et al. Among authors: sansom msp. Curr Opin Struct Biol. 2023 Jun;80:102589. doi: 10.1016/j.sbi.2023.102589. Epub 2023 Apr 9. Curr Opin Struct Biol. 2023. PMID: 37040671 Free article. Review.

3

The Energetics and Ion Coupling of Cholesterol Transport Through Patched1.

Ansell TB, Corey RA, Viti LV, Kinnebrew M, Rohatgi R, Siebold C, Sansom MSP. Ansell TB, et al. Among authors: sansom msp. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528445. doi: 10.1101/2023.02.14.528445. bioRxiv. 2023. Update in: Sci Adv. 2023 Aug 25;9(34):eadh1609. doi: 10.1126/sciadv.adh1609 PMID: 36824746 Free PMC article. Updated. Preprint.

4

Mapping structural and dynamic divergence across the MBOAT family.

Ansell TB, Healy M, Coupland CE, Sansom MSP, Siebold C. Ansell TB, et al. Among authors: sansom msp. Structure. 2024 Jul 11;32(7):1011-1022.e3. doi: 10.1016/j.str.2024.03.014. Epub 2024 Apr 17. Structure. 2024. PMID: 38636523 Free article.

5

The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2.

John LH, Naughton FB, Sansom MSP, Larsen AH. John LH, et al. Among authors: sansom msp. Membranes (Basel). 2023 Apr 4;13(4):408. doi: 10.3390/membranes13040408. Membranes (Basel). 2023. PMID: 37103835 Free PMC article.

6

Martini 3 Coarse-Grained Force Field for Carbohydrates.

Grünewald F, Punt MH, Jefferys EE, Vainikka PA, König M, Virtanen V, Meyer TA, Pezeshkian W, Gormley AJ, Karonen M, Sansom MSP, Souza PCT, Marrink SJ. Grünewald F, et al. Among authors: sansom msp. J Chem Theory Comput. 2022 Dec 13;18(12):7555-7569. doi: 10.1021/acs.jctc.2c00757. Epub 2022 Nov 7. J Chem Theory Comput. 2022. PMID: 36342474 Free PMC article.

7

Influence of electronic polarization on the binding of anions to a chloride-pumping rhodopsin.

Phan LX, Chamorro VC, Martinez-Seara H, Crain J, Sansom MSP, Tucker SJ. Phan LX, et al. Among authors: sansom msp. Biophys J. 2023 Apr 18;122(8):1548-1556. doi: 10.1016/j.bpj.2023.03.026. Epub 2023 Mar 21. Biophys J. 2023. PMID: 36945777 Free PMC article.

8

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl^- Channel.

Phan LX, Owji AP, Yang T, Crain J, Sansom MSP, Tucker SJ. Phan LX, et al. Among authors: sansom msp. J Chem Theory Comput. 2025 Jan 3. doi: 10.1021/acs.jctc.4c01039. Online ahead of print. J Chem Theory Comput. 2025. PMID: 39754290

9

Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery.

Conflitti P, Lyman E, Sansom MSP, Hildebrand PW, Gutiérrez-de-Terán H, Carloni P, Ansell TB, Yuan S, Barth P, Robinson AS, Tate CG, Gloriam D, Grzesiek S, Eddy MT, Prosser S, Limongelli V. Conflitti P, et al. Among authors: sansom msp. Nat Rev Drug Discov. 2025 Jan 2. doi: 10.1038/s41573-024-01083-3. Online ahead of print. Nat Rev Drug Discov. 2025. PMID: 39747671 Review.

10

The Role of Cholesterol in M2 Clustering and Viral Budding Explained.

Kolokouris D, Kalenderoglou IE, Duncan AL, Corey RA, Sansom MSP, Kolocouris A. Kolokouris D, et al. Among authors: sansom msp. J Chem Theory Comput. 2024 Nov 4. doi: 10.1021/acs.jctc.4c01026. Online ahead of print. J Chem Theory Comput. 2024. PMID: 39494590

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