Jacobsen SEW - Search Results

1

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC, Barkas N, Carrelha J, Giustacchini A, Mazzi S, Norfo R, Wu B, Aliouat A, Guerrero JA, Rodriguez-Meira A, Bouriez-Jones T, Macaulay IC, Jasztal M, Zhu G, Ni H, Robson MJ, Blakely RD, Mead AJ, Nerlov C, Ghevaert C, Jacobsen SEW. Luis TC, et al. Among authors: jacobsen sew. Nat Commun. 2023 Sep 28;14(1):6062. doi: 10.1038/s41467-023-41691-y. Nat Commun. 2023. PMID: 37770432 Free PMC article.

2

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C. Kirstetter P, et al. Nat Immunol. 2006 Oct;7(10):1048-56. doi: 10.1038/ni1381. Epub 2006 Sep 3. Nat Immunol. 2006. PMID: 16951689

3

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes.

Anderson K, Rusterholz C, Månsson R, Jensen CT, Bacos K, Zandi S, Sasaki Y, Nerlov C, Sigvardsson M, Jacobsen SE. Anderson K, et al. Blood. 2007 May 1;109(9):3697-705. doi: 10.1182/blood-2006-05-026021. Epub 2007 Jan 11. Blood. 2007. PMID: 17218387 Free article.

4

The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes.

Nilsson L, Edén P, Olsson E, Månsson R, Astrand-Grundström I, Strömbeck B, Theilgaard-Mönch K, Anderson K, Hast R, Hellström-Lindberg E, Samuelsson J, Bergh G, Nerlov C, Johansson B, Sigvardsson M, Borg A, Jacobsen SE. Nilsson L, et al. Blood. 2007 Oct 15;110(8):3005-14. doi: 10.1182/blood-2007-03-079368. Epub 2007 Jul 6. Blood. 2007. PMID: 17616640 Free article.

5

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

Nygren JM, Liuba K, Breitbach M, Stott S, Thorén L, Roell W, Geisen C, Sasse P, Kirik D, Björklund A, Nerlov C, Fleischmann BK, Jovinge S, Jacobsen SE. Nygren JM, et al. Nat Cell Biol. 2008 May;10(5):584-92. doi: 10.1038/ncb1721. Epub 2008 Apr 20. Nat Cell Biol. 2008. PMID: 18425115

6

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.

Weischenfeldt J, Damgaard I, Bryder D, Theilgaard-Mönch K, Thoren LA, Nielsen FC, Jacobsen SE, Nerlov C, Porse BT. Weischenfeldt J, et al. Genes Dev. 2008 May 15;22(10):1381-96. doi: 10.1101/gad.468808. Genes Dev. 2008. PMID: 18483223 Free PMC article.

7

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

Bröske AM, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M, Kuhl C, Enns A, Prinz M, Jaenisch R, Nerlov C, Leutz A, Andrade-Navarro MA, Jacobsen SE, Rosenbauer F. Bröske AM, et al. Nat Genet. 2009 Nov;41(11):1207-15. doi: 10.1038/ng.463. Epub 2009 Oct 4. Nat Genet. 2009. PMID: 19801979

8

Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.

Bereshchenko O, Mancini E, Moore S, Bilbao D, Månsson R, Luc S, Grover A, Jacobsen SE, Bryder D, Nerlov C. Bereshchenko O, et al. Cancer Cell. 2009 Nov 6;16(5):390-400. doi: 10.1016/j.ccr.2009.09.036. Cancer Cell. 2009. PMID: 19878871 Free article.

9

Persistent malignant stem cells in del(5q) myelodysplasia in remission.

Tehranchi R, Woll PS, Anderson K, Buza-Vidas N, Mizukami T, Mead AJ, Astrand-Grundström I, Strömbeck B, Horvat A, Ferry H, Dhanda RS, Hast R, Rydén T, Vyas P, Göhring G, Schlegelberger B, Johansson B, Hellström-Lindberg E, List A, Nilsson L, Jacobsen SE. Tehranchi R, et al. N Engl J Med. 2010 Sep 9;363(11):1025-37. doi: 10.1056/NEJMoa0912228. N Engl J Med. 2010. PMID: 20825315 Free article.

10

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.

Kharazi S, Mead AJ, Mansour A, Hultquist A, Böiers C, Luc S, Buza-Vidas N, Ma Z, Ferry H, Atkinson D, Reckzeh K, Masson K, Cammenga J, Rönnstrand L, Arai F, Suda T, Nerlov C, Sitnicka E, Jacobsen SE. Kharazi S, et al. Blood. 2011 Sep 29;118(13):3613-21. doi: 10.1182/blood-2010-06-289207. Epub 2011 Aug 2. Blood. 2011. PMID: 21813452 Free article.

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