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GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation.
Gauthier AG, Lin M, Zefi S, Kulkarni A, Thakur GA, Ashby CR Jr, Mantell LL. Gauthier AG, et al. Among authors: zefi s. Redox Biol. 2023 Apr;60:102614. doi: 10.1016/j.redox.2023.102614. Epub 2023 Jan 20. Redox Biol. 2023. PMID: 36717349 Free PMC article.