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PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia.
Pun SH, O'Neill KM, Edgar KS, Gill EK, Moez A, Naderi-Meshkin H, Malla SB, Hookham MB, Alsaggaf M, Madishetti VV, Botezatu B, King W, Brunssen C, Morawietz H, Dunne PD, Brazil DP, Medina RJ, Watson CJ, Grieve DJ. Pun SH, et al. Among authors: medina rj. Cells. 2023 Sep 6;12(18):2220. doi: 10.3390/cells12182220. Cells. 2023. PMID: 37759443 Free PMC article.
Enhanced Function of Induced Pluripotent Stem Cell-Derived Endothelial Cells Through ESM1 Signaling.
Vilà-González M, Kelaini S, Magee C, Caines R, Campbell D, Eleftheriadou M, Cochrane A, Drehmer D, Tsifaki M, O'Neill K, Pedrini E, Yang C, Medina R, McDonald D, Simpson D, Zampetaki A, Zeng L, Grieve D, Lois N, Stitt AW, Margariti A. Vilà-González M, et al. Stem Cells. 2019 Feb;37(2):226-239. doi: 10.1002/stem.2936. Epub 2018 Nov 17. Stem Cells. 2019. PMID: 30372556 Free PMC article.
The vasoreparative potential of endothelial colony-forming cells in the ischemic retina is enhanced by cibinetide, a non-hematopoietic erythropoietin mimetic.
O'Leary OE, Canning P, Reid E, Bertelli PM, McKeown S, Brines M, Cerami A, Du X, Xu H, Chen M, Dutton L, Brazil DP, Medina RJ, Stitt AW. O'Leary OE, et al. Among authors: medina rj. Exp Eye Res. 2019 May;182:144-155. doi: 10.1016/j.exer.2019.03.001. Epub 2019 Mar 12. Exp Eye Res. 2019. PMID: 30876881
NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes post-ischaemic revascularization.
O'Neill KM, Campbell DC, Edgar KS, Gill EK, Moez A, McLoughlin KJ, O'Neill CL, Dellett M, Hargey CJ, Abudalo RA, O'Hare M, Doyle P, Toh T, Khoo J, Wong J, McCrudden CM, Meloni M, Brunssen C, Morawietz H, Yoder MC, McDonald DM, Watson CJ, Stitt AW, Margariti A, Medina RJ, Grieve DJ. O'Neill KM, et al. Among authors: medina rj. Cardiovasc Res. 2020 Feb 1;116(2):393-405. doi: 10.1093/cvr/cvz090. Cardiovasc Res. 2020. PMID: 30937452
miR-130a activates the VEGFR2/STAT3/HIF1α axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia.
Guduric-Fuchs J, Pedrini E, Lechner J, Chambers SEJ, O'Neill CL, Mendes Lopes de Melo J, Pathak V, Church RH, McKeown S, Bojdo J, Mcloughlin KJ, Stitt AW, Medina RJ. Guduric-Fuchs J, et al. Among authors: medina rj. Mol Ther Nucleic Acids. 2021 Jan 20;23:968-981. doi: 10.1016/j.omtn.2021.01.015. eCollection 2021 Mar 5. Mol Ther Nucleic Acids. 2021. PMID: 33614244 Free PMC article.
Endothelial progenitors as tools to study vascular disease.
Medina RJ, O'Neill CL, O'Doherty TM, Wilson SE, Stitt AW. Medina RJ, et al. Stem Cells Int. 2012;2012:346735. doi: 10.1155/2012/346735. Epub 2012 Mar 15. Stem Cells Int. 2012. PMID: 22550504 Free PMC article.
57 results