Chen Z - Search Results

1

A broadly neutralizing antibody inhibits SARS-CoV-2 variants through a novel mechanism of disrupting spike trimer integrity.

Ma Y, Mao Q, Wang Y, Zhang Z, Chen J, Hao A, Rehati P, Wang Y, Wen Y, Lu L, Chen Z, Zhao J, Wu F, Sun L, Huang J. Ma Y, et al. Among authors: chen j, chen z. Cell Res. 2023 Dec;33(12):975-978. doi: 10.1038/s41422-023-00880-6. Epub 2023 Sep 27. Cell Res. 2023. PMID: 37758899 Free PMC article. No abstract available.

2

An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.

Liu Z, Xu W, Chen Z, Fu W, Zhan W, Gao Y, Zhou J, Zhou Y, Wu J, Wang Q, Zhang X, Hao A, Wu W, Zhang Q, Li Y, Fan K, Chen R, Jiang Q, Mayer CT, Schoofs T, Xie Y, Jiang S, Wen Y, Yuan Z, Wang K, Lu L, Sun L, Wang Q. Liu Z, et al. Among authors: chen z, chen r. Protein Cell. 2022 Sep;13(9):655-675. doi: 10.1007/s13238-021-00871-6. Epub 2021 Sep 23. Protein Cell. 2022. PMID: 34554412 Free PMC article.

3

The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.

Wang W, Wang Z, Yang X, Gao Y, Zhang X, Cao L, Dai A, Sun J, Sun L, Jiang L, Chen Z, Wang L. Wang W, et al. Among authors: chen z. Cell Discov. 2021 Oct 19;7(1):94. doi: 10.1038/s41421-021-00324-8. Cell Discov. 2021. PMID: 34663782 Free PMC article. No abstract available.

4

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.

Li C, Zhan W, Yang Z, Tu C, Hu G, Zhang X, Song W, Du S, Zhu Y, Huang K, Kong Y, Zhang M, Mao Q, Gu X, Zhang Y, Xie Y, Deng Q, Song Y, Chen Z, Lu L, Jiang S, Wu Y, Sun L, Ying T. Li C, et al. Among authors: chen z. Cell. 2022 Apr 14;185(8):1389-1401.e18. doi: 10.1016/j.cell.2022.03.009. Epub 2022 Mar 10. Cell. 2022. PMID: 35344711 Free PMC article.

5

A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.

Wang Y, Zhan W, Liu J, Wang Y, Zhang X, Zhang M, Han L, Ma Y, Lu L, Wen Y, Chen Z, Zhao J, Wu F, Sun L, Huang J. Wang Y, et al. Among authors: chen z. Cell Res. 2022 Sep;32(9):862-865. doi: 10.1038/s41422-022-00684-0. Epub 2022 Jun 29. Cell Res. 2022. PMID: 35768499 Free PMC article. No abstract available.

6

Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer.

Zhan W, Tian X, Zhang X, Xing S, Song W, Liu Q, Hao A, Hu Y, Zhang M, Ying T, Chen Z, Lan F, Sun L. Zhan W, et al. Among authors: chen z. J Virol. 2022 Aug 24;96(16):e0048022. doi: 10.1128/jvi.00480-22. Epub 2022 Aug 4. J Virol. 2022. PMID: 35924918 Free PMC article.

7

A 33-residue peptide tag increases solubility and stability of Escherichia coli produced single-chain antibody fragments.

Wang Y, Yuan W, Guo S, Li Q, Chen X, Li C, Liu Q, Sun L, Chen Z, Yuan Z, Luo C, Chen S, Tong S, Nassal M, Wen YM, Wang YX. Wang Y, et al. Among authors: chen z, chen s, chen x. Nat Commun. 2022 Aug 8;13(1):4614. doi: 10.1038/s41467-022-32423-9. Nat Commun. 2022. PMID: 35941164 Free PMC article.

8

Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies.

Wang Y, Zhang X, Ma Y, Wang Y, Zhan W, Zheng Q, Zhang M, Ji P, Liu M, Liu Q, Sun T, Zhu T, Wen Y, Sun L, Zhao J, Wu F, Chen Z, Huang J. Wang Y, et al. Among authors: chen z. Cell Discov. 2022 Oct 7;8(1):104. doi: 10.1038/s41421-022-00463-6. Cell Discov. 2022. PMID: 36207299 Free PMC article.

9

Fortuitous Somatic Mutations during Antibody Evolution Endow Broad Neutralization against SARS-CoV-2 Omicron Variants.

Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: chen z. bioRxiv [Preprint]. 2022 Dec 13:2022.12.12.520172. doi: 10.1101/2022.12.12.520172. bioRxiv. 2022. Update in: Cell Rep. 2023 May 30;42(5):112503. doi: 10.1016/j.celrep.2023.112503 PMID: 36561175 Free PMC article. Updated. Preprint.

10

Characterization of cross-reactive monoclonal antibodies against SARS-CoV-1 and SARS-CoV-2: Implication for rational design and development of pan-sarbecovirus vaccines and neutralizing antibodies.

Li S, Wu J, Jiang W, He H, Zhou Y, Wu W, Gao Y, Xie M, Xia A, He J, Zhang Q, Han Y, Wang N, Zhu G, Wang Q, Zhang Z, Mayer CT, Wang K, Wang X, Wang J, Chen Z, Jiang S, Sun L, Xia R, Wang Q. Li S, et al. Among authors: chen z. J Med Virol. 2023 Feb;95(2):e28440. doi: 10.1002/jmv.28440. J Med Virol. 2023. PMID: 36573441 Free PMC article.

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