Downes M - Search Results

1

Inhibiting Stromal Class I HDACs Curbs Pancreatic Cancer Progression.

Liang G, Oh TG, Hah N, Tiriac H, Shi Y, Truitt ML, Antal CE, Atkins AR, Li Y, Fraser C, Ng S, Pinto AFM, Nelson DC, Estepa G, Bashi S, Banayo E, Dai Y, Liddle C, Yu RT, Hunter T, Engle DD, Han H, Von Hoff DD, Downes M, Evans RM. Liang G, et al. Among authors: downes m. bioRxiv [Preprint]. 2023 Sep 14:2023.09.12.557260. doi: 10.1101/2023.09.12.557260. bioRxiv. 2023. Update in: Nat Commun. 2023 Dec 6;14(1):7791. doi: 10.1038/s41467-023-42178-6. PMID: 37745372 Free PMC article. Updated. Preprint.

2

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network.

Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Bookout AL, et al. Among authors: downes m. Cell. 2006 Aug 25;126(4):789-99. doi: 10.1016/j.cell.2006.06.049. Cell. 2006. PMID: 16923397 Free PMC article.

3

Look who's talking: nuclear receptors in the liver and gastrointestinal tract.

Downes M, Liddle C. Downes M, et al. Cell Metab. 2008 Mar;7(3):195-9. doi: 10.1016/j.cmet.2008.02.006. Cell Metab. 2008. PMID: 18316024 Free article.

4

Staying the distance: avoiding the proteasomal trap.

Downes M, Evans RM. Downes M, et al. Cancer Cell. 2008 Mar;13(3):184-5. doi: 10.1016/j.ccr.2008.02.014. Cancer Cell. 2008. PMID: 18328421 Free article.

5

Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance.

Fang S, Suh JM, Atkins AR, Hong SH, Leblanc M, Nofsinger RR, Yu RT, Downes M, Evans RM. Fang S, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3412-7. doi: 10.1073/pnas.1017707108. Epub 2011 Feb 7. Proc Natl Acad Sci U S A. 2011. PMID: 21300871 Free PMC article.

6

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Mihaylova MM, et al. Among authors: downes m. Cell. 2011 May 13;145(4):607-21. doi: 10.1016/j.cell.2011.03.043. Cell. 2011. PMID: 21565617 Free PMC article.

7

FXR and PXR: potential therapeutic targets in cholestasis.

Jonker JW, Liddle C, Downes M. Jonker JW, et al. Among authors: downes m. J Steroid Biochem Mol Biol. 2012 Jul;130(3-5):147-58. doi: 10.1016/j.jsbmb.2011.06.012. Epub 2011 Jul 20. J Steroid Biochem Mol Biol. 2012. PMID: 21801835 Free PMC article. Review.

8

Nuclear receptors as modulators of the tumor microenvironment.

Sherman MH, Downes M, Evans RM. Sherman MH, et al. Among authors: downes m. Cancer Prev Res (Phila). 2012 Jan;5(1):3-10. doi: 10.1158/1940-6207.CAPR-11-0528. Epub 2011 Dec 1. Cancer Prev Res (Phila). 2012. PMID: 22135047 Free PMC article. Review.

9

Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling.

Subramaniam N, Sherman MH, Rao R, Wilson C, Coulter S, Atkins AR, Evans RM, Liddle C, Downes M. Subramaniam N, et al. Among authors: downes m. Cancer Prev Res (Phila). 2012 Apr;5(4):553-61. doi: 10.1158/1940-6207.CAPR-12-0053. Epub 2012 Mar 9. Cancer Prev Res (Phila). 2012. PMID: 22406377 Free PMC article.

10

Nuclear receptors and AMPK: resetting metabolism.

Fan W, Downes M, Atkins A, Yu R, Evans RM. Fan W, et al. Among authors: downes m. Cold Spring Harb Symp Quant Biol. 2011;76:17-22. doi: 10.1101/sqb.2012.76.010470. Epub 2012 Mar 12. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22411605 Free PMC article. Review.

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