Nakhasi HL - Search Results

1

Leishmania major centrin knock-out parasites reprogram tryptophan metabolism to induce a pro-inflammatory response.

Oljuskin T, Azodi N, Volpedo G, Bhattacharya P, Markle HL, Hamano S, Matlashewski G, Satoskar AR, Gannavaram S, Nakhasi HL. Oljuskin T, et al. Among authors: nakhasi hl. iScience. 2023 Aug 29;26(9):107593. doi: 10.1016/j.isci.2023.107593. eCollection 2023 Sep 15. iScience. 2023. PMID: 37744403 Free PMC article.

2

Deletion of MIF gene from live attenuated LdCen^-/- parasites enhances protective CD4⁺ T cell immunity.

Fiuza JA, Gannavaram S, Gaze ST, de Ornellas LG, Alves ÉA, Ismail N, Nakhasi HL, Correa-Oliveira R. Fiuza JA, et al. Among authors: nakhasi hl. Sci Rep. 2023 May 5;13(1):7362. doi: 10.1038/s41598-023-34333-2. Sci Rep. 2023. PMID: 37147351 Free PMC article.

3

Field-Deployable Treatments For Leishmaniasis: Intrinsic Challenges, Recent Developments and Next Steps.

Pacheco-Fernandez T, Markle H, Verma C, Huston R, Gannavaram S, Nakhasi HL, Satoskar AR. Pacheco-Fernandez T, et al. Among authors: nakhasi hl. Res Rep Trop Med. 2023 Jul 20;14:61-85. doi: 10.2147/RRTM.S392606. eCollection 2023. Res Rep Trop Med. 2023. PMID: 37492219 Free PMC article. Review.

4

Dual-scRNA-seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection.

Karagiannis K, Gannavaram S, Verma C, Pacheco-Fernandez T, Bhattacharya P, Nakhasi HL, Satoskar AR. Karagiannis K, et al. Among authors: nakhasi hl. Cell Rep. 2023 Sep 26;42(9):113097. doi: 10.1016/j.celrep.2023.113097. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37682713 Free article.

5

Leishmania mexicana centrin knockout parasites promote M1-polarizing metabolic changes.

Volpedo G, Pacheco-Fernandez T, Oljuskin T, Markle HL, Azodi N, Hamano S, Matlashewski G, Gannavaram S, Nakhasi HL, Satoskar AR. Volpedo G, et al. Among authors: nakhasi hl. iScience. 2023 Aug 29;26(9):107594. doi: 10.1016/j.isci.2023.107594. eCollection 2023 Sep 15. iScience. 2023. PMID: 37744404 Free PMC article.

6

Leishmania mexicana promotes pain-reducing metabolomic reprogramming in cutaneous lesions.

Volpedo G, Oljuskin T, Cox B, Mercado Y, Askwith C, Azodi N, Bernier M, Nakhasi HL, Gannavaram S, Satoskar AR. Volpedo G, et al. Among authors: nakhasi hl. iScience. 2023 Nov 22;26(12):108502. doi: 10.1016/j.isci.2023.108502. eCollection 2023 Dec 15. iScience. 2023. PMID: 38125023 Free PMC article.

7

Manufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine.

Avishek K, Beg MA, Vats K, Singh AK, Dey R, Singh KP, Singh RK, Gannavaram S, Ramesh V, Mulla MSA, Bhatnagar U, Singh S, Nakhasi HL, Salotra P, Selvapandiyan A. Avishek K, et al. Among authors: nakhasi hl. Sci Rep. 2024 Jun 25;14(1):14636. doi: 10.1038/s41598-024-64592-6. Sci Rep. 2024. PMID: 38918456 Free PMC article.

8

Proteome profile of Leishmania donovani Centrin1^-/- parasite-infected human macrophage cell line and its implications in determining possible mechanisms of protective immunity.

Reyaz E, Tandon R, Beg MA, Dey R, Puri N, Salotra P, Nakhasi HL, Selvapandiyan A. Reyaz E, et al. Among authors: nakhasi hl. Microbes Infect. 2024 Jul-Aug;26(5-6):105340. doi: 10.1016/j.micinf.2024.105340. Epub 2024 Apr 23. Microbes Infect. 2024. PMID: 38663721

9

Identifying Rab2 Protein as a Key Interactor of Centrin1 Essential for Leishmania donovani Growth.

Roshanara, Tandon R, Baig MS, Das S, Srivastava R, Puri N, Nakhasi HL, Selvapandiyan A. Roshanara, et al. Among authors: nakhasi hl. ACS Infect Dis. 2024 Sep 13;10(9):3273-3288. doi: 10.1021/acsinfecdis.4c00351. Epub 2024 Aug 7. ACS Infect Dis. 2024. PMID: 39110117

10

Downregulation of IRF7-mediated type-I interferon response by LmCen^-/- parasites is necessary for protective immunity.

Sepahpour T, Alshaweesh J, Azodi N, Singh K, Ireland DDC, Valanezhad F, Nakamura R, Satoskar AR, Dey R, Hamano S, Nakhasi HL, Gannavaram S. Sepahpour T, et al. Among authors: nakhasi hl. NPJ Vaccines. 2024 Dec 19;9(1):250. doi: 10.1038/s41541-024-01032-6. NPJ Vaccines. 2024. PMID: 39702382 Free PMC article.

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