Conge MJ - Search Results

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Biodegradable Polyester Nanoparticle Vaccines Deliver Self-Amplifying mRNA in Mice at Low Doses.

Wilson DR, Tzeng SY, Rui Y, Neshat SY, Conge MJ, Luly KM, Wang E, Firestone JL, McAuliffe J, Maruggi G, Jalah R, Johnson R, Doloff JC, Green JJ. Wilson DR, et al. Among authors: conge mj. Adv Ther (Weinh). 2023 May;6(5):2200219. doi: 10.1002/adtp.202200219. Epub 2023 Feb 16. Adv Ther (Weinh). 2023. PMID: 37743930 Free PMC article.

Efficiency of Cytosolic Delivery with Poly(β-amino ester) Nanoparticles is Dependent on the Effective pK_a of the Polymer.

Routkevitch D, Sudhakar D, Conge M, Varanasi M, Tzeng SY, Wilson DR, Green JJ. Routkevitch D, et al. ACS Biomater Sci Eng. 2020 Jun 8;6(6):3411-3421. doi: 10.1021/acsbiomaterials.0c00271. Epub 2020 May 18. ACS Biomater Sci Eng. 2020. PMID: 33463158 Free PMC article.

High-throughput and high-content bioassay enables tuning of polyester nanoparticles for cellular uptake, endosomal escape, and systemic in vivo delivery of mRNA.

Rui Y, Wilson DR, Tzeng SY, Yamagata HM, Sudhakar D, Conge M, Berlinicke CA, Zack DJ, Tuesca A, Green JJ. Rui Y, et al. Sci Adv. 2022 Jan 7;8(1):eabk2855. doi: 10.1126/sciadv.abk2855. Epub 2022 Jan 5. Sci Adv. 2022. PMID: 34985952 Free PMC article.

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