Kim DY - Search Results

1

Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages.

Kim DY, Kandalaft H, Lowden MJ, Yang Q, Rossotti MA, Robotham A, Kelly JF, Hussack G, Schrag JD, Henry KA, Tanha J. Kim DY, et al. J Biol Chem. 2023 Nov;299(11):105278. doi: 10.1016/j.jbc.2023.105278. Epub 2023 Sep 22. J Biol Chem. 2023. PMID: 37742917 Free PMC article.

2

Antibody light chain variable domains and their biophysically improved versions for human immunotherapy.

Kim DY, To R, Kandalaft H, Ding W, van Faassen H, Luo Y, Schrag JD, St-Amant N, Hefford M, Hirama T, Kelly JF, MacKenzie R, Tanha J. Kim DY, et al. MAbs. 2014 Jan-Feb;6(1):219-35. doi: 10.4161/mabs.26844. MAbs. 2014. PMID: 24423624 Free PMC article.

3

Mutational approaches to improve the biophysical properties of human single-domain antibodies.

Kim DY, Hussack G, Kandalaft H, Tanha J. Kim DY, et al. Biochim Biophys Acta. 2014 Nov;1844(11):1983-2001. doi: 10.1016/j.bbapap.2014.07.008. Epub 2014 Jul 24. Biochim Biophys Acta. 2014. PMID: 25065345 Review.

4

A disulfide-stabilized human V_L single-domain antibody library is a source of soluble and highly thermostable binders.

Henry KA, Kandalaft H, Lowden MJ, Rossotti MA, van Faassen H, Hussack G, Durocher Y, Kim DY, Tanha J. Henry KA, et al. Among authors: kim dy. Mol Immunol. 2017 Oct;90:190-196. doi: 10.1016/j.molimm.2017.07.006. Epub 2017 Aug 15. Mol Immunol. 2017. PMID: 28820969

5

Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human V_H/V_L Single-Domain Antibodies from In Vitro Display Libraries.

Henry KA, Kim DY, Kandalaft H, Lowden MJ, Yang Q, Schrag JD, Hussack G, MacKenzie CR, Tanha J. Henry KA, et al. Among authors: kim dy. Front Immunol. 2017 Dec 12;8:1759. doi: 10.3389/fimmu.2017.01759. eCollection 2017. Front Immunol. 2017. PMID: 29375542 Free PMC article.

6

Evaluation of a noncanonical Cys40-Cys55 disulfide linkage for stabilization of single-domain antibodies.

Kim DY, Kandalaft H, Hussack G, Raphael S, Ding W, Kelly JF, Henry KA, Tanha J. Kim DY, et al. Protein Sci. 2019 May;28(5):881-888. doi: 10.1002/pro.3595. Epub 2019 Mar 14. Protein Sci. 2019. PMID: 30803088 Free PMC article.

7

Sodium dodecyl sulfate-polyacrylamide gel electrophoresis for screening nonaggregating human antibody heavy chain variable domains.

Kim DY, Tanha J. Kim DY, et al. Anal Biochem. 2010 Aug;403(1-2):117-9. doi: 10.1016/j.ab.2010.04.017. Epub 2010 Apr 18. Anal Biochem. 2010. PMID: 20406618

8

Solubility and stability engineering of human VH domains.

Kim DY, Ding W, Tanha J. Kim DY, et al. Methods Mol Biol. 2012;911:355-72. doi: 10.1007/978-1-61779-968-6_21. Methods Mol Biol. 2012. PMID: 22886262

9

Disulfide linkage engineering for improving biophysical properties of human VH domains.

Kim DY, Kandalaft H, Ding W, Ryan S, van Faassen H, Hirama T, Foote SJ, MacKenzie R, Tanha J. Kim DY, et al. Protein Eng Des Sel. 2012 Oct;25(10):581-9. doi: 10.1093/protein/gzs055. Epub 2012 Aug 30. Protein Eng Des Sel. 2012. PMID: 22942392

10

Stability of Proton Superoxide and its Superionic Transition Under High Pressure.

Wang Z, Yang W, Kim DY. Wang Z, et al. Among authors: kim dy. Adv Sci (Weinh). 2025 Jan 13:e2415387. doi: 10.1002/advs.202415387. Online ahead of print. Adv Sci (Weinh). 2025. PMID: 39805003

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