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TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, Cropper H, Jain P, Liu Q, Mehta SS, Zuckerman AJ, Xin M, Umans J, Huang J, Durairaj AS, Serrano GE, Beach TG, Greicius MD, James ML, Buckwalter MS, McReynolds MR, Rabinowitz JD, Andreasson KI. Wilson EN, et al. Among authors: le guen y. Nat Neurosci. 2024 May;27(5):873-885. doi: 10.1038/s41593-024-01610-w. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539014 Free PMC article.
KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers.
Belloy ME, Eger SJ, Le Guen Y, Napolioni V, Deters KD, Yang HS, Scelsi MA, Porter T, James SN, Wong A, Schott JM, Sperling RA, Laws SM, Mormino EC, He Z, Han SS, Altmann A, Greicius MD; A4 Study Team; Insight 46 Study Team; Australian Imaging Biomarkers and Lifestyle (AIBL) Study; Alzheimer's Disease Neuroimaging Initiative. Belloy ME, et al. Among authors: le guen y. Neurobiol Aging. 2021 May;101:123-129. doi: 10.1016/j.neurobiolaging.2021.01.008. Epub 2021 Jan 23. Neurobiol Aging. 2021. PMID: 33610961 Free PMC article.
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