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CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Huang S, Shahine A, Cheng TY, Chen YL, Ng SW, Balaji GR, Farquhar R, Gras S, Hardman CS, Altman JD, Tahiri N, Minnaard AJ, Ogg GS, Mayfield JA, Rossjohn J, Moody DB. Huang S, et al. Among authors: hardman cs. Cell. 2023 Oct 12;186(21):4583-4596.e13. doi: 10.1016/j.cell.2023.08.022. Epub 2023 Sep 18. Cell. 2023. PMID: 37725977 Free PMC article.
Innate Lymphocyte Mechanisms in Skin Diseases.
Chen YL, Hardman CS, Yadava K, Ogg G. Chen YL, et al. Among authors: hardman cs. Annu Rev Immunol. 2020 Apr 26;38:171-202. doi: 10.1146/annurev-immunol-082919-093554. Annu Rev Immunol. 2020. PMID: 32340577 Review.
CD1a promotes systemic manifestations of skin inflammation.
Hardman CS, Chen YL, Wegrecki M, Ng SW, Murren R, Mangat D, Silva JP, Munro R, Chan WY, O'Dowd V, Doyle C, Mori P, Popplewell A, Rossjohn J, Lightwood D, Ogg GS. Hardman CS, et al. Nat Commun. 2022 Dec 7;13(1):7535. doi: 10.1038/s41467-022-35071-1. Nat Commun. 2022. PMID: 36477177 Free PMC article.
CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.
Hardman CS, Chen YL, Salimi M, Jarrett R, Johnson D, Järvinen VJ, Owens RJ, Repapi E, Cousins DJ, Barlow JL, McKenzie ANJ, Ogg G. Hardman CS, et al. Sci Immunol. 2017 Dec 22;2(18):eaan5918. doi: 10.1126/sciimmunol.aan5918. Sci Immunol. 2017. PMID: 29273672 Free PMC article.
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation.
Chen YL, Ng JSW, Ottakandathil Babu R, Woo J, Nahler J, Hardman CS, Kurupati P, Nussbaum L, Gao F, Dong T, Ladell K, Price DA, Duncan DA, Johnson D, Gileadi U, Koohy H, Ogg GS. Chen YL, et al. Among authors: hardman cs. Sci Immunol. 2023 Jun 8;8(84):eadd9232. doi: 10.1126/sciimmunol.add9232. Epub 2023 Jun 2. Sci Immunol. 2023. PMID: 37267382 Free PMC article.
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase.
Jarrett R, Salio M, Lloyd-Lavery A, Subramaniam S, Bourgeois E, Archer C, Cheung KL, Hardman C, Chandler D, Salimi M, Gutowska-Owsiak D, de la Serna JB, Fallon PG, Jolin H, Mckenzie A, Dziembowski A, Podobas EI, Bal W, Johnson D, Moody DB, Cerundolo V, Ogg G. Jarrett R, et al. Sci Transl Med. 2016 Feb 10;8(325):325ra18. doi: 10.1126/scitranslmed.aad6833. Sci Transl Med. 2016. PMID: 26865566 Free PMC article.
26 results