Shulman GI - Search Results

1

MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis.

Park J, Hall C, Hubbard B, LaMoia T, Gaspar R, Nasiri A, Li F, Zhang H, Kim J, Haeusler RA, Accili D, Shulman GI, Yu H, Choi E. Park J, et al. Among authors: shulman gi. Diabetes. 2023 Dec 1;72(12):1781-1794. doi: 10.2337/db23-0314. Diabetes. 2023. PMID: 37725942 Free PMC article.

2

Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.

Gaspar RC, Lyu K, Hubbard BT, Leitner BP, Luukkonen PK, Hirabara SM, Sakuma I, Nasiri A, Zhang D, Kahn M, Cline GW, Pauli JR, Perry RJ, Petersen KF, Shulman GI. Gaspar RC, et al. Among authors: shulman gi. Diabetologia. 2023 Mar;66(3):567-578. doi: 10.1007/s00125-022-05838-8. Epub 2022 Dec 1. Diabetologia. 2023. PMID: 36456864 Free PMC article.

3

Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo.

Hubbard BT, LaMoia TE, Goedeke L, Gaspar RC, Galsgaard KD, Kahn M, Mason GF, Shulman GI. Hubbard BT, et al. Among authors: shulman gi. Cell Metab. 2023 Jan 3;35(1):212-226.e4. doi: 10.1016/j.cmet.2022.11.011. Epub 2022 Dec 13. Cell Metab. 2023. PMID: 36516861 Free PMC article.

4

Author Correction: Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner.

Pajvani UB, Shawber CJ, Samuel VT, Birkenfeld AL, Shulman GI, Kitajewski J, Accili D. Pajvani UB, et al. Among authors: shulman gi. Nat Med. 2024 Feb;30(2):604. doi: 10.1038/s41591-023-02695-9. Nat Med. 2024. PMID: 38041001 No abstract available.

5

O-GlcNAc modification in endothelial cells modulates adiposity via fat absorption from the intestine in mice.

Ohgaku S, Ida S, Ohashi N, Morino K, Ishikado A, Yanagimachi T, Murata K, Sato D, Ugi S, Nasiri A, Shulman GI, Maegawa H, Kume S, Fujita Y. Ohgaku S, et al. Among authors: shulman gi. Heliyon. 2024 Jul 14;10(14):e34490. doi: 10.1016/j.heliyon.2024.e34490. eCollection 2024 Jul 30. Heliyon. 2024. PMID: 39130439 Free PMC article.

6

Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation.

LaMoia TE, Hubbard BT, Guerra MT, Nasiri A, Sakuma I, Kahn M, Zhang D, Goodman RP, Nathanson MH, Sancak Y, Perelis M, Mootha VK, Shulman GI. LaMoia TE, et al. Among authors: shulman gi. Cell Metab. 2024 Oct 1;36(10):2329-2340.e4. doi: 10.1016/j.cmet.2024.07.016. Epub 2024 Aug 16. Cell Metab. 2024. PMID: 39153480

7

Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.

Gaspar RC, Sakuma I, Nasiri A, Hubbard BT, LaMoia TE, Leitner BP, Tep S, Xi Y, Green EM, Ullman JC, Petersen KF, Shulman GI. Gaspar RC, et al. Among authors: shulman gi. Am J Physiol Endocrinol Metab. 2024 Oct 1;327(4):E524-E532. doi: 10.1152/ajpendo.00175.2024. Epub 2024 Aug 22. Am J Physiol Endocrinol Metab. 2024. PMID: 39171753

8

Effect of Weight Loss on Skeletal Muscle Bioactive Lipids in People With Obesity and Type 2 Diabetes.

Petersen MC, Yoshino M, Smith GI, Gaspar RC, Kahn M, Samovski D, Shulman GI, Klein S. Petersen MC, et al. Among authors: shulman gi. Diabetes. 2024 Dec 1;73(12):2055-2064. doi: 10.2337/db24-0083. Diabetes. 2024. PMID: 39264820

9

Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptor^T1150 phosphorylation pathway.

Xu W, Zhang D, Ma Y, Gaspar RC, Kahn M, Nasiri A, Murray S, Samuel VT, Shulman GI. Xu W, et al. Among authors: shulman gi. Cell Rep. 2024 Oct 22;43(10):114746. doi: 10.1016/j.celrep.2024.114746. Epub 2024 Sep 19. Cell Rep. 2024. PMID: 39302831 Free article.

10

High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis.

Goedeke L, Strober JW, Suh R, Paolella LM, Li X, Rogers JC, Petersen MC, Nasiri AR, Casals G, Kahn M, Cline GW, Samuel VT, Shulman GI, Vatner DF. Goedeke L, et al. Among authors: shulman gi. iScience. 2024 Oct 15;27(11):111175. doi: 10.1016/j.isci.2024.111175. eCollection 2024 Nov 15. iScience. 2024. PMID: 39524330 Free PMC article.

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