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Page 1
Histone mutations in cancer.
Espinoza Pereira KN, Shan J, Licht JD, Bennett RL. Espinoza Pereira KN, et al. Among authors: licht jd. Biochem Soc Trans. 2023 Oct 31;51(5):1749-1763. doi: 10.1042/BST20210567. Biochem Soc Trans. 2023. PMID: 37721138 Free PMC article.
Genetic variation drives cancer cell adaptation to ECM stiffness.
Wang TC, Sawhney S, Morgan D, Bennett RL, Rashmi R, Estecio MR, Brock A, Singh I, Baer CF, Licht JD, Lele TP. Wang TC, et al. Among authors: licht jd. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2403062121. doi: 10.1073/pnas.2403062121. Epub 2024 Sep 20. Proc Natl Acad Sci U S A. 2024. PMID: 39302966 Free PMC article.
Low muscle mass is associated with a higher risk of all-cause and cardiovascular disease-specific mortality in cancer survivors.
Zhang D, Spiropoulos KA, Wijayabahu A, Christou DD, Karanth SD, Anton SD, Leeuwenburgh C, Liang M, Wheeler M, Yang D, Livingstone AP, Mankowski RT, Cheng TD, Zhang H, Siegel EM, Penedo FJ, Licht JD, Braithwaite D. Zhang D, et al. Among authors: licht jd. Nutrition. 2023 Mar;107:111934. doi: 10.1016/j.nut.2022.111934. Epub 2022 Dec 10. Nutrition. 2023. PMID: 36563433 Free PMC article.
The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma.
Berardi A, Kaestner CL, Ghitti M, Quilici G, Cocomazzi P, Li J, Ballabio F, Zucchelli C, Knapp S, Licht JD, Musco G. Berardi A, et al. Among authors: licht jd. Nucleic Acids Res. 2024 Dec 5:gkae1121. doi: 10.1093/nar/gkae1121. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39656918
Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs.
Saintilnord WN, Hegazy YA, Chesnutt K, Eckstein M, Cassidy RN, Dhahri H, Bennett RL, Melters DP, Lopes E, Fu Z, Lau K, Chandler DP, Poirier MG, Dalal Y, Licht JD, Fondufe-Mittendorf Y. Saintilnord WN, et al. Among authors: licht jd. bioRxiv [Preprint]. 2024 Nov 21:2024.11.18.624207. doi: 10.1101/2024.11.18.624207. bioRxiv. 2024. PMID: 39605447 Free PMC article. Preprint.
KDM6A regulates immune response genes in multiple myeloma.
Dupéré-Richer D, Riva A, Barwick BG, Maji S, Casellas Román H, Li J, De U, Sobh A, Quickstad G, Piper C, Kulis M, Ezponda T, Martín-Subero JI, Tonon G, Zhang W, Mitsiades CS, Boise LH, Bennett RL, Licht JD. Dupéré-Richer D, et al. Among authors: licht jd. Blood. 2024 Oct 3;144(14):1508-1520. doi: 10.1182/blood.2024024518. Blood. 2024. PMID: 39046770
Recruitment of FBXO22 for targeted degradation of NSD2.
Nie DY, Tabor JR, Li J, Kutera M, St-Germain J, Hanley RP, Wolf E, Paulakonis E, Kenney TMG, Duan S, Shrestha S, Owens DDG, Maitland MER, Pon A, Szewczyk M, Lamberto AJ, Menes M, Li F, Penn LZ, Barsyte-Lovejoy D, Brown NG, Barsotti AM, Stamford AW, Collins JL, Wilson DJ, Raught B, Licht JD, James LI, Arrowsmith CH. Nie DY, et al. Among authors: licht jd. Nat Chem Biol. 2024 Dec;20(12):1597-1607. doi: 10.1038/s41589-024-01660-y. Epub 2024 Jul 4. Nat Chem Biol. 2024. PMID: 38965384
223 results