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Page 1
Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum.
Bennett JM, Ward KE, Muir RK, Kabeche S, Yoo E, Yeo T, Lam G, Zhang H, Almaliti J, Berger G, Faucher FF, Lin G, Gerwick WH, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: kabeche s. ACS Infect Dis. 2023 Oct 13;9(10):2036-2047. doi: 10.1021/acsinfecdis.3c00310. Epub 2023 Sep 15. ACS Infect Dis. 2023. PMID: 37712594 Free PMC article.
Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS.
Kabeche S, Aida J, Akther T, Ichikawa T, Ochida A, Pulkoski-Gross MJ, Smith M, Humphries PS, Yeh E. Kabeche S, et al. Bioorg Med Chem Lett. 2021 Jun 1;41:127978. doi: 10.1016/j.bmcl.2021.127978. Epub 2021 Mar 22. Bioorg Med Chem Lett. 2021. PMID: 33766764
Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets.
Bennett JM, Narwal SK, Kabeche S, Abegg D, Thathy V, Hackett F, Yeo T, Li VL, Muir R, Faucher F, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: kabeche s. Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006. Epub 2024 Aug 12. Cell Chem Biol. 2024. PMID: 39137783
A picomolar inhibitor of the Plasmodium falciparum IPP pathway.
Kabeche S, Braukmann T, Doenier J, Meister T, Yeh E. Kabeche S, et al. Antimicrob Agents Chemother. 2024 Aug 7;68(8):e0123823. doi: 10.1128/aac.01238-23. Epub 2024 Jul 22. Antimicrob Agents Chemother. 2024. PMID: 39037239
Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets.
Bennett JM, Narwal SK, Kabeche S, Abegg D, Hackett F, Yeo T, Li VL, Muir RK, Faucher FF, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: kabeche s. bioRxiv [Preprint]. 2024 Jan 11:2024.01.11.575224. doi: 10.1101/2024.01.11.575224. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006 PMID: 38260474 Free PMC article. Updated. Preprint.
Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
Gilman MS, Moin SM, Mas V, Chen M, Patel NK, Kramer K, Zhu Q, Kabeche SC, Kumar A, Palomo C, Beaumont T, Baxa U, Ulbrandt ND, Melero JA, Graham BS, McLellan JS. Gilman MS, et al. Among authors: kabeche sc. PLoS Pathog. 2015 Jul 10;11(7):e1005035. doi: 10.1371/journal.ppat.1005035. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26161532 Free PMC article.