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The laminin-keratin link shields the nucleus from mechanical deformation and signalling.
Kechagia Z, Sáez P, Gómez-González M, Canales B, Viswanadha S, Zamarbide M, Andreu I, Koorman T, Beedle AEM, Elosegui-Artola A, Derksen PWB, Trepat X, Arroyo M, Roca-Cusachs P. Kechagia Z, et al. Among authors: andreu i. Nat Mater. 2023 Nov;22(11):1409-1420. doi: 10.1038/s41563-023-01657-3. Epub 2023 Sep 14. Nat Mater. 2023. PMID: 37709930 Free PMC article.
Periosteum-derived mesenchymal progenitor cells in engineered implants promote fracture healing in a critical-size defect rat model.
González-Gil AB, Lamo-Espinosa JM, Muiños-López E, Ripalda-Cemboráin P, Abizanda G, Valdés-Fernández J, López-Martínez T, Flandes-Iparraguirre M, Andreu I, Elizalde MR, Stuckensen K, Groll J, De-Juan-Pardo EM, Prósper F, Granero-Moltó F. González-Gil AB, et al. Among authors: andreu i. J Tissue Eng Regen Med. 2019 May;13(5):742-752. doi: 10.1002/term.2821. Epub 2019 Mar 21. J Tissue Eng Regen Med. 2019. PMID: 30785671
Rigidity sensing and adaptation through regulation of integrin types.
Elosegui-Artola A, Bazellières E, Allen MD, Andreu I, Oria R, Sunyer R, Gomm JJ, Marshall JF, Jones JL, Trepat X, Roca-Cusachs P. Elosegui-Artola A, et al. Among authors: andreu i. Nat Mater. 2014 Jun;13(6):631-7. doi: 10.1038/nmat3960. Epub 2014 May 4. Nat Mater. 2014. PMID: 24793358 Free PMC article.
Role of Myocardial Collagen in Severe Aortic Stenosis With Preserved Ejection Fraction and Symptoms of Heart Failure.
Echegaray K, Andreu I, Lazkano A, Villanueva I, Sáenz A, Elizalde MR, Echeverría T, López B, Garro A, González A, Zubillaga E, Solla I, Sanz I, González J, Elósegui-Artola A, Roca-Cusachs P, Díez J, Ravassa S, Querejeta R. Echegaray K, et al. Among authors: andreu i. Rev Esp Cardiol (Engl Ed). 2017 Oct;70(10):832-840. doi: 10.1016/j.rec.2016.12.038. Epub 2017 Feb 16. Rev Esp Cardiol (Engl Ed). 2017. PMID: 28215921 English, Spanish.
Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores.
Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P. Elosegui-Artola A, et al. Among authors: andreu i. Cell. 2017 Nov 30;171(6):1397-1410.e14. doi: 10.1016/j.cell.2017.10.008. Epub 2017 Oct 26. Cell. 2017. PMID: 29107331 Free article.
Nuclear deformation mediates liver cell mechanosensing in cirrhosis.
Guixé-Muntet S, Ortega-Ribera M, Wang C, Selicean S, Andreu I, Kechagia JZ, Fondevila C, Roca-Cusachs P, Dufour JF, Bosch J, Berzigotti A, Gracia-Sancho J. Guixé-Muntet S, et al. Among authors: andreu i. JHEP Rep. 2020 Jul 17;2(5):100145. doi: 10.1016/j.jhepr.2020.100145. eCollection 2020 Oct. JHEP Rep. 2020. PMID: 32939447 Free PMC article.
Mechanical force application to the nucleus regulates nucleocytoplasmic transport.
Andreu I, Granero-Moya I, Chahare NR, Clein K, Molina-Jordán M, Beedle AEM, Elosegui-Artola A, Abenza JF, Rossetti L, Trepat X, Raveh B, Roca-Cusachs P. Andreu I, et al. Nat Cell Biol. 2022 Jun;24(6):896-905. doi: 10.1038/s41556-022-00927-7. Epub 2022 Jun 9. Nat Cell Biol. 2022. PMID: 35681009 Free PMC article.
106 results