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DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Alzheimers Res Ther. 2024 Feb 8;16(1):29. doi: 10.1186/s13195-024-01390-2.
Alzheimers Res Ther. 2024.
PMID: 38326859
Free PMC article.
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates neuroinflammation and amyloid-β deposition in Alzheimer's disease The Ohio State University College of Medicine.
Daily KP, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan MH, Carafice C, Krause K, McNamara A, Hamilton K, Houle S, Gupta S, Gupta GA, Madhu S, Fitzgerald J, Saadey AA, Laster B, Yan P, Webb A, Zhang X, Pietrzak M, Kokiko-Cochran ON, Ghoneim HE, Amer AO.
Daily KP, et al. Among authors: saadey aa.
bioRxiv [Preprint]. 2023 Sep 1:2023.08.30.555526. doi: 10.1101/2023.08.30.555526.
bioRxiv. 2023.
PMID: 37693600
Free PMC article.
Preprint.
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Rebalancing TGFβ1/BMP signals in exhausted T cells unlocks responsiveness to immune checkpoint blockade therapy.
Saadey AA, Yousif A, Osborne N, Shahinfar R, Chen YL, Laster B, Rajeev M, Bauman P, Webb A, Ghoneim HE.
Saadey AA, et al.
Nat Immunol. 2023 Feb;24(2):280-294. doi: 10.1038/s41590-022-01384-y. Epub 2022 Dec 21.
Nat Immunol. 2023.
PMID: 36543960
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