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HIV-1 binds dynein directly to hijack microtubule transport machinery.
Badieyan S, Lichon D, Andreas MP, Gillies JP, Peng W, Shi J, DeSantis ME, Aiken CR, Böcking T, Giessen TW, Campbell EM, Cianfrocco MA. Badieyan S, et al. Among authors: desantis me. bioRxiv [Preprint]. 2023 Dec 2:2023.08.29.555335. doi: 10.1101/2023.08.29.555335. bioRxiv. 2023. PMID: 37693451 Free PMC article. Preprint.
LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes.
Htet ZM, Gillies JP, Baker RW, Leschziner AE, DeSantis ME, Reck-Peterson SL. Htet ZM, et al. Among authors: desantis me. Nat Cell Biol. 2020 May;22(5):518-525. doi: 10.1038/s41556-020-0506-z. Epub 2020 Apr 27. Nat Cell Biol. 2020. PMID: 32341549 Free PMC article.
Nde1 and Ndel1: Outstanding Mysteries in Dynein-Mediated Transport.
Garrott SR, Gillies JP, DeSantis ME. Garrott SR, et al. Among authors: desantis me. Front Cell Dev Biol. 2022 Apr 12;10:871935. doi: 10.3389/fcell.2022.871935. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35493069 Free PMC article. Review.
CCSer2 gates dynein activity at the cell periphery.
Zang JL, Gibson D, Zheng AM, Shi W, Gillies JP, Stein C, Drerup CM, DeSantis ME. Zang JL, et al. Among authors: desantis me. bioRxiv [Preprint]. 2024 Jun 14:2024.06.13.598865. doi: 10.1101/2024.06.13.598865. bioRxiv. 2024. PMID: 38915497 Free PMC article. Preprint.
CryoEM shows the active dynein complex on microtubules.
Garrott SR, DeSantis ME. Garrott SR, et al. Among authors: desantis me. Trends Biochem Sci. 2023 Apr;48(4):315-316. doi: 10.1016/j.tibs.2023.01.007. Epub 2023 Feb 6. Trends Biochem Sci. 2023. PMID: 36754682
30 results