Bremer A - Search Results

1

Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions.

Farag M, Borcherds WM, Bremer A, Mittag T, Pappu RV. Farag M, et al. Among authors: bremer a. Nat Commun. 2023 Sep 8;14(1):5527. doi: 10.1038/s41467-023-41274-x. Nat Commun. 2023. PMID: 37684240 Free PMC article.

2

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains.

Martin EW, Holehouse AS, Peran I, Farag M, Incicco JJ, Bremer A, Grace CR, Soranno A, Pappu RV, Mittag T. Martin EW, et al. Among authors: bremer a. Science. 2020 Feb 7;367(6478):694-699. doi: 10.1126/science.aaw8653. Science. 2020. PMID: 32029630 Free PMC article.

3

Microfluidic characterization of macromolecular liquid-liquid phase separation.

Bremer A, Mittag T, Heymann M. Bremer A, et al. Lab Chip. 2020 Nov 10;20(22):4225-4234. doi: 10.1039/d0lc00613k. Lab Chip. 2020. PMID: 33057557 Free PMC article.

4

How do intrinsically disordered protein regions encode a driving force for liquid-liquid phase separation?

Borcherds W, Bremer A, Borgia MB, Mittag T. Borcherds W, et al. Among authors: bremer a. Curr Opin Struct Biol. 2021 Apr;67:41-50. doi: 10.1016/j.sbi.2020.09.004. Epub 2020 Oct 15. Curr Opin Struct Biol. 2021. PMID: 33069007 Free PMC article. Review.

5

Deciphering how naturally occurring sequence features impact the phase behaviours of disordered prion-like domains.

Bremer A, Farag M, Borcherds WM, Peran I, Martin EW, Pappu RV, Mittag T. Bremer A, et al. Nat Chem. 2022 Feb;14(2):196-207. doi: 10.1038/s41557-021-00840-w. Epub 2021 Dec 20. Nat Chem. 2022. PMID: 34931046 Free PMC article.

6

Quantifying Coexistence Concentrations in Multi-Component Phase-Separating Systems Using Analytical HPLC.

Bremer A, Posey AE, Borgia MB, Borcherds WM, Farag M, Pappu RV, Mittag T. Bremer A, et al. Biomolecules. 2022 Oct 14;12(10):1480. doi: 10.3390/biom12101480. Biomolecules. 2022. PMID: 36291688 Free PMC article.

7

Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations.

Farag M, Cohen SR, Borcherds WM, Bremer A, Mittag T, Pappu RV. Farag M, et al. Among authors: bremer a. Nat Commun. 2022 Dec 13;13(1):7722. doi: 10.1038/s41467-022-35370-7. Nat Commun. 2022. PMID: 36513655 Free PMC article.

8

Crowder titrations enable the quantification of driving forces for macromolecular phase separation.

Chauhan G, Bremer A, Dar F, Mittag T, Pappu RV. Chauhan G, et al. Among authors: bremer a. Biophys J. 2024 Jun 4;123(11):1376-1392. doi: 10.1016/j.bpj.2023.09.006. Epub 2023 Sep 16. Biophys J. 2024. PMID: 37717144

9

Design of intrinsically disordered protein variants with diverse structural properties.

Pesce F, Bremer A, Tesei G, Hopkins JB, Grace CR, Mittag T, Lindorff-Larsen K. Pesce F, et al. Among authors: bremer a. bioRxiv [Preprint]. 2023 Oct 24:2023.10.22.563461. doi: 10.1101/2023.10.22.563461. bioRxiv. 2023. Update in: Sci Adv. 2024 Aug 30;10(35):eadm9926. doi: 10.1126/sciadv.adm9926 PMID: 37961110 Free PMC article. Updated. Preprint.

10

Design of intrinsically disordered protein variants with diverse structural properties.

Pesce F, Bremer A, Tesei G, Hopkins JB, Grace CR, Mittag T, Lindorff-Larsen K. Pesce F, et al. Among authors: bremer a. Sci Adv. 2024 Aug 30;10(35):eadm9926. doi: 10.1126/sciadv.adm9926. Epub 2024 Aug 28. Sci Adv. 2024. PMID: 39196930 Free PMC article.

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