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Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.
Ozyerli-Goknar E, Kala EY, Aksu AC, Bulut I, Cingöz A, Nizamuddin S, Biniossek M, Seker-Polat F, Morova T, Aztekin C, Kung SHY, Syed H, Tuncbag N, Gönen M, Philpott M, Cribbs AP, Acilan C, Lack NA, Onder TT, Timmers HTM, Bagci-Onder T. Ozyerli-Goknar E, et al. Among authors: timmers htm. Cell Commun Signal. 2023 Nov 16;21(1):328. doi: 10.1186/s12964-023-01335-6. Cell Commun Signal. 2023. PMID: 37974198 Free PMC article.
Herpesviruses mimic zygotic genome activation to promote viral replication.
Neugebauer E, Walter S, Tan J, Drayman N, Franke V, van Gent M, Pennisi S, Veratti P, Stein KS, Welker I, Tay S, Verjans GMGM, Timmers HTM, Akalin A, Landthaler M, Ensser A, Wyler E, Full F. Neugebauer E, et al. Among authors: timmers htm. Nat Commun. 2025 Jan 16;16(1):710. doi: 10.1038/s41467-025-55928-5. Nat Commun. 2025. PMID: 39814710 Free PMC article.
Epigenetic modulation via the C-terminal tail of H2A.Z.
Imre L, Nánási P Jr, Benhamza I, Enyedi KN, Mocsár G, Bosire R, Hegedüs É, Niaki EF, Csóti Á, Darula Z, Csősz É, Póliska S, Scholtz B, Mező G, Bacsó Z, Timmers HTM, Kusakabe M, Balázs M, Vámosi G, Ausio J, Cheung P, Tóth K, Tremethick D, Harata M, Szabó G. Imre L, et al. Among authors: timmers htm. Nat Commun. 2024 Oct 24;15(1):9171. doi: 10.1038/s41467-024-53514-9. Nat Commun. 2024. PMID: 39448645 Free PMC article.
The roles of TAF1 in neuroscience and beyond.
Crombie EM, Cleverley K, Timmers HTM, Fisher EMC. Crombie EM, et al. Among authors: timmers htm. R Soc Open Sci. 2024 Sep 25;11(9):240790. doi: 10.1098/rsos.240790. eCollection 2024 Sep. R Soc Open Sci. 2024. PMID: 39323550 Free PMC article. Review.
Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory.
Michelatti D, Beyes S, Bernardis C, Negri ML, Morelli L, Bediaga NG, Poli V, Fagnocchi L, Lago S, D'Annunzio S, Cona N, Gaspardo I, Bianchi A, Jovetic J, Gianesello M, Turdo A, D'Accardo C, Gaggianesi M, Dori M, Forcato M, Crispatzu G, Rada-Iglesias A, Sosa MS, Timmers HTM, Bicciato S, Todaro M, Tiberi L, Zippo A. Michelatti D, et al. Among authors: timmers htm. Nat Commun. 2024 Mar 19;15(1):2198. doi: 10.1038/s41467-024-46524-0. Nat Commun. 2024. PMID: 38503727 Free PMC article.
107 results