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347 results

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Page 1
Combined Mek inhibition and Pparg activation Eradicates Muscle Invasive Bladder cancer in a Mouse Model of BBN-induced Carcinogenesis.
Tate T, Plumber SA, Al-Ahmadie H, Chen X, Choi W, Lu C, Viny A, Batourina E, Gartensson K, Alija B, Molotkov A, Wiessner G, McKiernan J, McConkey D, Dinney C, Czerniak B, Mendelsohn CL. Tate T, et al. Among authors: czerniak b. bioRxiv [Preprint]. 2023 Aug 21:2023.08.19.553961. doi: 10.1101/2023.08.19.553961. bioRxiv. 2023. PMID: 37662238 Free PMC article. Preprint.
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.
Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, Hinoue T, Laird PW, Hoadley KA, Akbani R, Castro MAA, Gibb EA, Kanchi RS, Gordenin DA, Shukla SA, Sanchez-Vega F, Hansel DE, Czerniak BA, Reuter VE, Su X, de Sa Carvalho B, Chagas VS, Mungall KL, Sadeghi S, Pedamallu CS, Lu Y, Klimczak LJ, Zhang J, Choo C, Ojesina AI, Bullman S, Leraas KM, Lichtenberg TM, Wu CJ, Schultz N, Getz G, Meyerson M, Mills GB, McConkey DJ; TCGA Research Network; Weinstein JN, Kwiatkowski DJ, Lerner SP. Robertson AG, et al. Among authors: czerniak ba. Cell. 2017 Oct 19;171(3):540-556.e25. doi: 10.1016/j.cell.2017.09.007. Epub 2017 Oct 5. Cell. 2017. PMID: 28988769 Free PMC article.
Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis.
Lee S, Bondaruk J, Wang Y, Chen H, Lee JG, Majewski T, Mullen RD, Cogdell D, Chen J, Wang Z, Yao H, Kus P, Jeong J, Lee I, Choi W, Navai N, Guo C, Dinney C, Baggerly K, Mendelsohn C, McConkey D, Behringer RR, Kimmel M, Wei P, Czerniak B. Lee S, et al. Among authors: czerniak b. Cell Rep. 2024 May 28;43(5):114146. doi: 10.1016/j.celrep.2024.114146. Epub 2024 Apr 25. Cell Rep. 2024. PMID: 38676926 Free PMC article.
Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.
Steinmetz AR, Pierce M, Martini A, Tholomier C, Manyam G, Chen Y, Sood A, Duplisea JJ, Johnson BA, Czerniak BA, Lee BH, Jagannath C, Yla-Herttuala S, Parker NR, McConkey DJ, Dinney CP, Mokkapati S. Steinmetz AR, et al. Among authors: czerniak ba. Front Immunol. 2024 Nov 4;15:1387229. doi: 10.3389/fimmu.2024.1387229. eCollection 2024. Front Immunol. 2024. PMID: 39559365 Free PMC article.
METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics.
Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi MP, Lazcano R, Yamashita K, Xu Z, Pei G, Cho KS, Chu Y, Sinjab A, Peng F, Yan X, Han G, Wang R, Dai E, Dai Y, Czerniak BA, Futreal A, Maitra A, Lazar A, Kadara H, Jazaeri AA, Cheng X, Ajani J, Gao J, Hu J, Wang L. Jiang J, et al. Among authors: czerniak ba. Nat Commun. 2024 Aug 25;15(1):7312. doi: 10.1038/s41467-024-51708-9. Nat Commun. 2024. PMID: 39181865 Free PMC article.
Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer.
Plumber SA, Tate T, Al-Ahmadie H, Chen X, Choi W, Basar M, Lu C, Viny A, Batourina E, Li J, Gretarsson K, Alija B, Molotkov A, Wiessner G, Lee BHL, McKiernan J, McConkey DJ, Dinney C, Czerniak B, Mendelsohn CL. Plumber SA, et al. Among authors: czerniak b. Nat Commun. 2024 Aug 2;15(1):6538. doi: 10.1038/s41467-024-50678-2. Nat Commun. 2024. PMID: 39095358 Free PMC article.
Inferring Bladder Cancer Evolution from Mucosal field Effects by Whole-Organ Spatial Mutational, Proteomic, and Metabolomic Mapping.
Czerniak B, Lee S, Jung SY, Kus P, Bondaruk J, Lee J, Jaksik R, Putluri N, Dinh K, Cogdell D, Chen H, Wang Y, Chen J, Nevai N, Dinney C, Mendelsohn C, McConkey D, Behringer R, Guo C, Wei P, Kimmel M. Czerniak B, et al. Res Sq [Preprint]. 2024 Apr 10:rs.3.rs-3994376. doi: 10.21203/rs.3.rs-3994376/v1. Res Sq. 2024. PMID: 38659962 Free PMC article. Preprint.
347 results