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Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes.
Saint-Dizier F, Matthews TP, Gregson AM, Prevet H, McHardy T, Colombano G, Saville H, Rowlands M, Ewens C, McAndrew PC, Tomlin K, Guillotin D, Mak GW, Drosopoulos K, Poursaitidis I, Burke R, van Montfort R, Linardopoulos S, Collins I. Saint-Dizier F, et al. Among authors: gregson am. J Med Chem. 2023 Feb 23;66(4):2622-2645. doi: 10.1021/acs.jmedchem.2c01591. Epub 2023 Feb 7. J Med Chem. 2023. PMID: 36749938 Free PMC article.
A method for high-throughput image-based antifungal screening.
Sabburg R, Gregson A, Urquhart AS, Aitken EAB, Smith L, Thatcher LF, Gardiner DM. Sabburg R, et al. Among authors: gregson a. J Microbiol Methods. 2021 Nov;190:106342. doi: 10.1016/j.mimet.2021.106342. Epub 2021 Oct 5. J Microbiol Methods. 2021. PMID: 34619139
International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation.
Martinu T, Koutsokera A, Benden C, Cantu E, Chambers D, Cypel M, Edelman J, Emtiazjoo A, Fisher AJ, Greenland JR, Hayes D Jr, Hwang D, Keller BC, Lease ED, Perch M, Sato M, Todd JL, Verleden S, von der Thüsen J, Weigt SS, Keshavjee S; bronchoalveolar lavage standardization workgroup. Martinu T, et al. J Heart Lung Transplant. 2020 Nov;39(11):1171-1190. doi: 10.1016/j.healun.2020.07.006. Epub 2020 Jul 15. J Heart Lung Transplant. 2020. PMID: 32773322 Free PMC article.
Identification and SAR exploration of a novel series of Legumain inhibitors.
Eddie SL, Gregson A, Graham E, Burton S, Harrison T, Burden R, Scott CJ, Mullan PB, Williams R. Eddie SL, et al. Among authors: gregson a. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1546-1548. doi: 10.1016/j.bmcl.2019.03.019. Epub 2019 Mar 29. Bioorg Med Chem Lett. 2019. PMID: 31005445
76 results