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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, Spies M, Brown DD, Lee AV, Schopfer F, Freeman BA, Neumann CA. Hong L, et al. Among authors: woodcock sr. bioRxiv [Preprint]. 2023 Aug 14:2023.08.11.552990. doi: 10.1101/2023.08.11.552990. bioRxiv. 2023. Update in: Redox Biol. 2023 Oct;66:102856. doi: 10.1016/j.redox.2023.102856. PMID: 37645906 Free PMC article. Updated. Preprint.
Nitro-fatty acid formation and signaling.
Freeman BA, Baker PR, Schopfer FJ, Woodcock SR, Napolitano A, d'Ischia M. Freeman BA, et al. Among authors: woodcock sr. J Biol Chem. 2008 Jun 6;283(23):15515-9. doi: 10.1074/jbc.R800004200. Epub 2008 Feb 19. J Biol Chem. 2008. PMID: 18285326 Free PMC article. Review. No abstract available.
Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury.
Cole MP, Rudolph TK, Khoo NK, Motanya UN, Golin-Bisello F, Wertz JW, Schopfer FJ, Rudolph V, Woodcock SR, Bolisetty S, Ali MS, Zhang J, Chen YE, Agarwal A, Freeman BA, Bauer PM. Cole MP, et al. Among authors: woodcock sr. Circ Res. 2009 Nov 6;105(10):965-72. doi: 10.1161/CIRCRESAHA.109.199075. Epub 2009 Sep 24. Circ Res. 2009. PMID: 19797175 Free PMC article.
Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids.
Groeger AL, Cipollina C, Cole MP, Woodcock SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ. Groeger AL, et al. Among authors: woodcock sr. Nat Chem Biol. 2010 Jun;6(6):433-41. doi: 10.1038/nchembio.367. Epub 2010 May 2. Nat Chem Biol. 2010. PMID: 20436486 Free PMC article.
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.
Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Ylä-Herttuala S, Freeman BA, Levonen AL. Kansanen E, et al. Among authors: woodcock sr. J Biol Chem. 2011 Apr 22;286(16):14019-27. doi: 10.1074/jbc.M110.190710. Epub 2011 Feb 25. J Biol Chem. 2011. PMID: 21357422 Free PMC article.
49 results