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Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Rasool RU, O'Connor CM, Das CK, Alhusayan M, Verma BK, Islam S, Frohner IE, Deng Q, Mitchell-Velasquez E, Sangodkar J, Ahmed A, Linauer S, Mudrak I, Rainey J, Zawacki KP, Suhan TK, Callahan CG, Rebernick R, Natesan R, Siddiqui J, Sauter G, Thomas D, Wang S, Taylor DJ, Simon R, Cieslik M, Chinnaiyan AM, Busino L, Ogris E, Narla G, Asangani IA. Rasool RU, et al. Among authors: thomas d. Nat Commun. 2023 Aug 29;14(1):5253. doi: 10.1038/s41467-023-40760-6. Nat Commun. 2023. PMID: 37644036 Free PMC article.
Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment.
Morikawa A, Li J, Ulintz P, Cheng X, Apfel A, Robinson D, Hopkins A, Kumar-Sinha C, Wu YM, Serhan H, Verbal K, Thomas D, Hayes DF, Chinnaiyan AM, Baladandayuthapani V, Heth J, Soellner MB, Merajver SD, Merrill N. Morikawa A, et al. Among authors: thomas d. Cancer Res Commun. 2023 Jun 21;3(6):1093-1103. doi: 10.1158/2767-9764.CRC-22-0492. eCollection 2023 Jun. Cancer Res Commun. 2023. PMID: 37377606 Free PMC article.
KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.
Lu S, Kim HS, Cao Y, Bedi K, Zhao L, Narayanan IV, Magnuson B, Gu Y, Yang J, Yi Z, Babaniamansour S, Shameon S, Xu C, Paulsen MT, Qiu P, Jeyarajan S, Ljungman M, Thomas D, Dou Y, Crawford H, di Magliano MP, Ge K, Yang B, Shi J. Lu S, et al. Among authors: thomas d. Int J Cancer. 2023 Aug 1;153(3):552-570. doi: 10.1002/ijc.34528. Epub 2023 May 4. Int J Cancer. 2023. PMID: 37140208 Free PMC article.
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Rhim AD, Oberstein PE, Thomas DH, Mirek ET, Palermo CF, Sastra SA, Dekleva EN, Saunders T, Becerra CP, Tattersall IW, Westphalen CB, Kitajewski J, Fernandez-Barrena MG, Fernandez-Zapico ME, Iacobuzio-Donahue C, Olive KP, Stanger BZ. Rhim AD, et al. Among authors: thomas dh. Cancer Cell. 2014 Jun 16;25(6):735-47. doi: 10.1016/j.ccr.2014.04.021. Epub 2014 May 22. Cancer Cell. 2014. PMID: 24856585 Free PMC article.
GRAIL1 stabilizes misfolded mutant p53 through a ubiquitin ligase-independent, chaperone regulatory function.
Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. Ray P, et al. Among authors: thomas d. Mol Cancer Res. 2024 Jul 17. doi: 10.1158/1541-7786.MCR-24-0361. Online ahead of print. Mol Cancer Res. 2024. PMID: 39018356
Head and neck squamous cell carcinoma in pregnant women.
Eliassen AM, Hauff SJ, Tang AL, Thomas DH, McHugh JB, Walline HM, Stoerker J, Maxwell JH, Worden FP, Eisbruch A, Czerwinski MJ, Papagerakis SM, Chepeha DB, Bradford CR, Hanauer DA, Carey TE, Prince ME. Eliassen AM, et al. Head Neck. 2013 Mar;35(3):335-42. doi: 10.1002/hed.22973. Epub 2012 Mar 16. Head Neck. 2013. PMID: 22422571 Free PMC article.
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