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Page 1
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Chitty JL, Yam M, Perryman L, Parker AL, Skhinas JN, Setargew YFI, Mok ETY, Tran E, Grant RD, Latham SL, Pereira BA, Ritchie SC, Murphy KJ, Trpceski M, Findlay AD, Melenec P, Filipe EC, Nadalini A, Velayuthar S, Major G, Wyllie K, Papanicolaou M, Ratnaseelan S, Phillips PA, Sharbeen G, Youkhana J, Russo A, Blackwell A, Hastings JF, Lucas MC, Chambers CR, Reed DA, Stoehr J, Vennin C, Pidsley R, Zaratzian A, Da Silva AM, Tayao M, Charlton B, Herrmann D, Nobis M, Clark SJ, Biankin AV, Johns AL, Croucher DR, Nagrial A, Gill AJ, Grimmond SM; Australian Pancreatic Cancer Genome Initiative (APGI); Australian Pancreatic Cancer Matrix Atlas (APMA); Pajic M, Timpson P, Jarolimek W, Cox TR. Chitty JL, et al. Among authors: filipe ec. Nat Cancer. 2023 Sep;4(9):1326-1344. doi: 10.1038/s43018-023-00614-y. Epub 2023 Aug 28. Nat Cancer. 2023. PMID: 37640930 Free PMC article.
Charting the unexplored extracellular matrix in cancer.
Filipe EC, Chitty JL, Cox TR. Filipe EC, et al. Int J Exp Pathol. 2018 Apr;99(2):58-76. doi: 10.1111/iep.12269. Epub 2018 Apr 19. Int J Exp Pathol. 2018. PMID: 29671911 Free PMC article. Review.
Recent advances in understanding the complexities of metastasis.
Chitty JL, Filipe EC, Lucas MC, Herrmann D, Cox TR, Timpson P. Chitty JL, et al. Among authors: filipe ec. F1000Res. 2018 Aug 1;7:F1000 Faculty Rev-1169. doi: 10.12688/f1000research.15064.2. eCollection 2018. F1000Res. 2018. PMID: 30135716 Free PMC article. Review.
The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development.
Chitty JL, Skhinas JN, Filipe EC, Wang S, Cupello CR, Grant RD, Yam M, Papanicolaou M, Major G, Zaratzian A, Da Silva AM, Tayao M, Vennin C, Timpson P, Madsen CD, Cox TR. Chitty JL, et al. Among authors: filipe ec. Cancer Rep (Hoboken). 2020 Feb;3(1):e1209. doi: 10.1002/cnr2.1209. Epub 2019 Aug 1. Cancer Rep (Hoboken). 2020. PMID: 32671954 Free PMC article.
In Vitro 3D Models of Tunable Stiffness.
Filipe EC, Parker AL, Cadell AL, Major G, Croucher DR, Cox TR. Filipe EC, et al. Methods Mol Biol. 2021;2294:27-42. doi: 10.1007/978-1-0716-1350-4_3. Methods Mol Biol. 2021. PMID: 33742392
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.
Murphy KJ, Reed DA, Vennin C, Conway JRW, Nobis M, Yin JX, Chambers CR, Pereira BA, Lee V, Filipe EC, Trpceski M, Ritchie S, Lucas MC, Warren SC, Skhinas JN, Magenau A, Metcalf XL, Stoehr J, Major G, Parkin A, Bidanel R, Lyons RJ, Zaratzian A, Tayao M, Da Silva A, Abdulkhalek L; Australian Pancreatic Genome Initiative (APGI); Australian Pancreatic Cancer Matrix Atlas (APMA); Gill AJ, Johns AL, Biankin AV, Samra J, Grimmond SM, Chou A, Goetz JG, Samuel MS, Lyons JG, Burgess A, Caldon CE, Horvath LG, Daly RJ, Gadegaard N, Wang Y, Sansom OJ, Morton JP, Cox TR, Pajic M, Herrmann D, Timpson P. Murphy KJ, et al. Among authors: filipe ec. Sci Adv. 2021 Oct;7(40):eabh0363. doi: 10.1126/sciadv.abh0363. Epub 2021 Sep 29. Sci Adv. 2021. PMID: 34586840 Free PMC article.
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis.
Papanicolaou M, Parker AL, Yam M, Filipe EC, Wu SZ, Chitty JL, Wyllie K, Tran E, Mok E, Nadalini A, Skhinas JN, Lucas MC, Herrmann D, Nobis M, Pereira BA, Law AMK, Castillo L, Murphy KJ, Zaratzian A, Hastings JF, Croucher DR, Lim E, Oliver BG, Mora FV, Parker BL, Gallego-Ortega D, Swarbrick A, O'Toole S, Timpson P, Cox TR. Papanicolaou M, et al. Among authors: filipe ec. Nat Commun. 2022 Aug 6;13(1):4587. doi: 10.1038/s41467-022-32255-7. Nat Commun. 2022. PMID: 35933466 Free PMC article.
Bovine and human endometrium-derived hydrogels support organoid culture from healthy and cancerous tissues.
Jamaluddin MFB, Ghosh A, Ingle A, Mohammed R, Ali A, Bahrami M, Kaiko G, Gibb Z, Filipe EC, Cox TR, Boulton A, O'Sullivan R, Ius Y, Karakoti A, Vinu A, Nahar P, Jaaback K, Bansal V, Tanwar PS. Jamaluddin MFB, et al. Among authors: filipe ec. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2208040119. doi: 10.1073/pnas.2208040119. Epub 2022 Oct 24. Proc Natl Acad Sci U S A. 2022. PMID: 36279452 Free PMC article.
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