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Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab')2 fragments.
Findlay-Wilson S, Easterbrook L, Smith S, Pope N, Aldridge M, Humphries G, Schuhmann H, Ngabo D, Rayner E, Otter A, Coleman T, Hicks B, Halkerston R, Apostolakis K, Taylor S, Fotheringham S, Horton A, CanoCejas I, Wand M, Tree JA, Sutton M, Graham V, Hewson R, Dowall S. Findlay-Wilson S, et al. Among authors: easterbrook l. Sci Rep. 2023 Aug 25;13(1):13912. doi: 10.1038/s41598-023-40277-4. Sci Rep. 2023. PMID: 37626085 Free PMC article.
Capturing the natural diversity of the human antibody response against vaccinia virus.
Lantto J, Haahr Hansen M, Rasmussen SK, Steinaa L, Poulsen TR, Duggan J, Dennis M, Naylor I, Easterbrook L, Bregenholt S, Haurum J, Jensen A. Lantto J, et al. Among authors: easterbrook l. J Virol. 2011 Feb;85(4):1820-33. doi: 10.1128/JVI.02127-10. Epub 2010 Dec 8. J Virol. 2011. PMID: 21147924 Free PMC article.
Catheterized guinea pigs infected with Ebola Zaire virus allows safer sequential sampling to determine the pharmacokinetic profile of a phosphatidylserine-targeting monoclonal antibody.
Dowall S, Taylor I, Yeates P, Smith L, Rule A, Easterbrook L, Bruce C, Cook N, Corbin-Lickfett K, Empig C, Schlunegger K, Graham V, Dennis M, Hewson R. Dowall S, et al. Among authors: easterbrook l. Antiviral Res. 2013 Feb;97(2):108-11. doi: 10.1016/j.antiviral.2012.11.003. Epub 2012 Nov 16. Antiviral Res. 2013. PMID: 23165089
Antiviral Screening of Multiple Compounds against Ebola Virus.
Dowall SD, Bewley K, Watson RJ, Vasan SS, Ghosh C, Konai MM, Gausdal G, Lorens JB, Long J, Barclay W, Garcia-Dorival I, Hiscox J, Bosworth A, Taylor I, Easterbrook L, Pitman J, Summers S, Chan-Pensley J, Funnell S, Vipond J, Charlton S, Haldar J, Hewson R, Carroll MW. Dowall SD, et al. Among authors: easterbrook l. Viruses. 2016 Oct 27;8(11):277. doi: 10.3390/v8110277. Viruses. 2016. PMID: 27801778 Free PMC article.
The effect of heat-treatment on SARS-CoV-2 viability and detection.
Burton J, Love H, Richards K, Burton C, Summers S, Pitman J, Easterbrook L, Davies K, Spencer P, Killip M, Cane P, Bruce C, Roberts ADG. Burton J, et al. Among authors: easterbrook l. J Virol Methods. 2021 Apr;290:114087. doi: 10.1016/j.jviromet.2021.114087. Epub 2021 Jan 28. J Virol Methods. 2021. PMID: 33515663 Free PMC article.
Dose-Dependent Response to Infection with Ebola Virus in the Ferret Model and Evidence of Viral Evolution in the Eye.
Watson RJ, Tree J, Fotheringham SA, Hall Y, Dong X, Steeds K, Gouriet J, Salguero FJ, Burton C, Pitman J, Easterbrook L, Richards KS, Burton J, Bewley K, Bruce C, Hiscox JA, Carroll MW, Funnell SGP. Watson RJ, et al. Among authors: easterbrook l. J Virol. 2021 Nov 23;95(24):e0083321. doi: 10.1128/JVI.00833-21. Epub 2021 Sep 29. J Virol. 2021. PMID: 34586862 Free PMC article.
Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit proteins.
Findlay-Wilson S, Easterbrook L, Smith S, Pope N, Humphries G, Schuhmann H, Ngabo D, Rayner E, Otter AD, Coleman T, Hicks B, Graham VA, Halkerston R, Apostolakis K, Taylor S, Fotheringham S, Horton A, Tree JA, Wand M, Hewson R, Dowall SD. Findlay-Wilson S, et al. Among authors: easterbrook l. Antiviral Res. 2022 Jul;203:105332. doi: 10.1016/j.antiviral.2022.105332. Epub 2022 May 6. Antiviral Res. 2022. PMID: 35533779 Free PMC article.
26 results