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TET1 Regulates Skeletal Stem-Cell Mediated Cartilage Regeneration.
Pandey A, Hoover M, Singla M, Bedi Y, Storaci H, Goodman SB, Chan C, Bhutani N. Pandey A, et al. Among authors: chan c. Arthritis Rheumatol. 2024 Feb;76(2):216-230. doi: 10.1002/art.42678. Epub 2023 Dec 10. Arthritis Rheumatol. 2024. PMID: 37610277
Pharmacological rescue of diabetic skeletal stem cell niches.
Tevlin R, Seo EY, Marecic O, McArdle A, Tong X, Zimdahl B, Malkovskiy A, Sinha R, Gulati G, Li X, Wearda T, Morganti R, Lopez M, Ransom RC, Duldulao CR, Rodrigues M, Nguyen A, Januszyk M, Maan Z, Paik K, Yapa KS, Rajadas J, Wan DC, Gurtner GC, Snyder M, Beachy PA, Yang F, Goodman SB, Weissman IL, Chan CK, Longaker MT. Tevlin R, et al. Among authors: chan ck. Sci Transl Med. 2017 Jan 11;9(372):eaag2809. doi: 10.1126/scitranslmed.aag2809. Sci Transl Med. 2017. PMID: 28077677 Free PMC article.
Identification of the Human Skeletal Stem Cell.
Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT. Chan CKF, et al. Among authors: chan k. Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029. Cell. 2018. PMID: 30241615 Free PMC article.
Articular cartilage regeneration by activated skeletal stem cells.
Murphy MP, Koepke LS, Lopez MT, Tong X, Ambrosi TH, Gulati GS, Marecic O, Wang Y, Ransom RC, Hoover MY, Steininger H, Zhao L, Walkiewicz MP, Quarto N, Levi B, Wan DC, Weissman IL, Goodman SB, Yang F, Longaker MT, Chan CKF. Murphy MP, et al. Among authors: chan ckf. Nat Med. 2020 Oct;26(10):1583-1592. doi: 10.1038/s41591-020-1013-2. Epub 2020 Aug 17. Nat Med. 2020. PMID: 32807933 Free PMC article.
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
Ambrosi TH, Sinha R, Steininger HM, Hoover MY, Murphy MP, Koepke LS, Wang Y, Lu WJ, Morri M, Neff NF, Weissman IL, Longaker MT, Chan CK. Ambrosi TH, et al. Elife. 2021 Jul 19;10:e66063. doi: 10.7554/eLife.66063. Elife. 2021. PMID: 34280086 Free PMC article.
Aged skeletal stem cells generate an inflammatory degenerative niche.
Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, Brewer RE, Mascharak S, Lu L, Ajanaku O, Conley SD, Seita J, Morri M, Neff NF, Sahoo D, Yang F, Weissman IL, Longaker MT, Chan CKF. Ambrosi TH, et al. Nature. 2021 Sep;597(7875):256-262. doi: 10.1038/s41586-021-03795-7. Epub 2021 Aug 11. Nature. 2021. PMID: 34381212 Free PMC article.
Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs.
Goodnough LH, Ambrosi TH, Steininger HM, Butler MGK, Hoover MY, Choo H, Van Rysselberghe NL, Bellino MJ, Bishop JA, Gardner MJ, Chan CKF. Goodnough LH, et al. Front Endocrinol (Lausanne). 2022 Aug 25;13:924927. doi: 10.3389/fendo.2022.924927. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36093067 Free PMC article.
Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration.
Andrew TW, Koepke LS, Wang Y, Lopez M, Steininger H, Struck D, Boyko T, Ambrosi TH, Tong X, Sun Y, Gulati GS, Murphy MP, Marecic O, Tevlin R, Schallmoser K, Strunk D, Seita J, Goodman SB, Yang F, Longaker MT, Yang GP, Chan CKF. Andrew TW, et al. Nat Commun. 2022 Oct 30;13(1):6491. doi: 10.1038/s41467-022-34063-5. Nat Commun. 2022. PMID: 36310174 Free PMC article.
A Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue.
Zhao L, Lee AS, Sasagawa K, Sokol J, Wang Y, Ransom RC, Zhao X, Ma C, Steininger HM, Koepke LS, Borrelli MR, Brewer RE, Lee LLY, Huang X, Ambrosi TH, Sinha R, Hoover MY, Seita J, Weissman IL, Wu JC, Wan DC, Xiao J, Longaker MT, Nguyen PK, Chan CKF. Zhao L, et al. Among authors: chan ckf. Arterioscler Thromb Vasc Biol. 2023 Jul;43(7):1262-1277. doi: 10.1161/ATVBAHA.122.317943. Epub 2023 Apr 13. Arterioscler Thromb Vasc Biol. 2023. PMID: 37051932 Free PMC article.
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