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Page 1
Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity.
Brodeur MN, Dopeso H, Zhu Y, Longhini ALF, Gazzo A, Sun S, Koche R, Qu R, Hamard PJ, Bykov Y, Green H, Chiappinelli KB, Ozsoy MA, Basili T, Gardner R, Walderich S, DeStanchina E, Greenbaum B, Gönen M, Weigelt B, Zamarin D. Brodeur MN, et al. Among authors: greenbaum b. bioRxiv [Preprint]. 2023 Aug 11:2023.08.08.552544. doi: 10.1101/2023.08.08.552544. bioRxiv. 2023. Update in: Sci Adv. 2024 Dec 6;10(49):eadk4851. doi: 10.1126/sciadv.adk4851 PMID: 37609261 Free PMC article. Updated. Preprint.
T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
Bozkus CC, Brown M, Velazquez L, Thomas M, Wilson EA, O'Donnell T, Ruchnewitz D, Geertz D, Bykov Y, Kodysh J, Oguntuyo KY, Roudko V, Hoyos D, Srivastava KD, Kleiner G, Alshammary H, Karekar N, McClain C, Gopal R, Nie K, Del Valle D, Delbeau-Zagelbaum D, Rodriguez D, Setal J; Mount Sinai COVID-19 Biobank Team; Carroll E, Wiesendanger M, Gulko PS, Charney A, Merad M, Kim-Schulze S, Lee B, Wajnberg A, Simon V, Greenbaum BD, Chowell D, Vabret N, Luksza M, Bhardwaj N. Bozkus CC, et al. Among authors: greenbaum bd. bioRxiv [Preprint]. 2024 Oct 24:2024.10.23.619918. doi: 10.1101/2024.10.23.619918. bioRxiv. 2024. PMID: 39484455 Free PMC article. Preprint.
Cancer cells co-evolve with retrotransposons to mitigate viral mimicry.
Sun S, Hong J, You E, Tsanov KM, Chacon-Barahona J, Gioacchino AD, Hoyos D, Li H, Jiang H, Ly H, Marhon S, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD. Sun S, et al. bioRxiv [Preprint]. 2023 May 20:2023.05.19.541456. doi: 10.1101/2023.05.19.541456. bioRxiv. 2023. PMID: 37292765 Free PMC article. Preprint.
Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers.
Boruah N, Hoyos D, Moses R, Hausler R, Desai H, Le AN, Good M, Kelly G, Raghavakaimal A, Tayeb M, Narasimhamurthy M, Doucette A, Gabriel P, Feldman MJ, Park J, de Rodas ML, Schalper KA, Goldfarb SB, Nayak A, Levine AJ, Greenbaum BD, Maxwell KN. Boruah N, et al. Among authors: greenbaum bd. bioRxiv [Preprint]. 2024 Apr 5:2024.04.03.588009. doi: 10.1101/2024.04.03.588009. bioRxiv. 2024. PMID: 38617260 Free PMC article. Preprint.
Intratumoral T-cell composition predicts epcoritamab-based treatment efficacy in B-cell non-Hodgkin lymphomas.
Falchi L, Rahman J, Melendez L, Douglas M, Amador WR, Hamlin P, Kumar A, Hoehn D, Lin YH, Gao Q, Roshal M, Ewalt MD, Dogan A, Greenbaum B, Salles GA, Vardhana SA. Falchi L, et al. Among authors: greenbaum b. medRxiv [Preprint]. 2024 Jul 5:2024.07.02.24309792. doi: 10.1101/2024.07.02.24309792. medRxiv. 2024. PMID: 39006439 Free PMC article. Preprint.
Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity.
Brodeur MN, Dopeso H, Zhu Y, Longhini ALF, Gazzo A, Sun S, Koche RP, Qu R, Rosenberg L, Hamard PJ, Bykov Y, Green H, Gusain L, Chiappinelli KB, Ozsoy MA, Chui MH, Basili T, Gardner R, Walderich S, DeStanchina E, Greenbaum B, Gönen M, Vabret N, Weigelt B, Zamarin D. Brodeur MN, et al. Among authors: greenbaum b. Sci Adv. 2024 Dec 6;10(49):eadk4851. doi: 10.1126/sciadv.adk4851. Epub 2024 Dec 4. Sci Adv. 2024. PMID: 39630912 Free PMC article.
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.
Sun S, You E, Hong J, Hoyos D, Del Priore I, Tsanov KM, Mattagajasingh O, Di Gioacchino A, Marhon SA, Chacon-Barahona J, Li H, Jiang H, Hozeifi S, Rosas-Bringas O, Xu KH, Song Y, Lang ER, Rojas AS, Nieman LT, Patel BK, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, Zenklusen D, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD. Sun S, et al. Among authors: greenbaum bd. Immunity. 2024 Dec 10;57(12):2879-2894.e11. doi: 10.1016/j.immuni.2024.10.015. Epub 2024 Nov 21. Immunity. 2024. PMID: 39577413 Free article.
Molecular Heterogeneity and Immune Infiltration Drive Clinical Outcomes in Upper Tract Urothelial Carcinoma.
Kim K, Alam SM, Kuo F, Chen Z, Yip W, Katims AB, Chu C, Lenis AT, Hu W, Gokturk Ozcan G, Chen JF, Firouzi S, Elhanati Y, Clinton TN, Aulitzky A, Almassi N, Fujii Y, Tracey AT, Reisz PA, Budhu S, Vuong L, Eichholz J, Woo HJ, Nogueira L, Gao SP, Scherz A, Aggen DH, Rosenberg JE, Pietzak EJ, Seshan V, Greenbaum B, Becker A, Akin O, Iyer G, Al-Ahmadie H, Hakimi AA, Merghoub T, Solit DB, Coleman JA. Kim K, et al. Among authors: greenbaum b. Eur Urol. 2024 Nov 15:S0302-2838(24)02686-1. doi: 10.1016/j.eururo.2024.10.024. Online ahead of print. Eur Urol. 2024. PMID: 39550333 Free article.
Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer.
You E, Danaher P, Lu C, Sun S, Zou L, Phillips IE, Rojas AS, Ho NI, Song Y, Raabe MJ, Xu KH, Richieri PM, Li H, Aston N, Porter RL, Patel BK, Nieman LT, Schurman N, Hudson BM, North K, Church SE, Deshpande V, Liss AS, Kim TK, Cui Y, Kim Y, Greenbaum BD, Aryee MJ, Ting DT. You E, et al. Among authors: greenbaum bd. Cell. 2024 Dec 12;187(25):7232-7247.e23. doi: 10.1016/j.cell.2024.09.024. Epub 2024 Oct 8. Cell. 2024. PMID: 39383862
Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer.
Hosseini A, Lindholm HT, Chen R, Mehdipour P, Marhon SA, Ishak CA, Moore PC, Classon M, Di Gioacchino A, Greenbaum B, De Carvalho DD. Hosseini A, et al. Among authors: greenbaum b. Cell Rep. 2024 Feb 27;43(2):113684. doi: 10.1016/j.celrep.2024.113684. Epub 2024 Jan 22. Cell Rep. 2024. PMID: 38261511 Free article.
132 results