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Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice.
Sandovici I, Fernandez-Twinn DS, Campbell N, Cooper WN, Sekita Y, Zvetkova I, Ferland-McCollough D, Prosser HM, Oyama LM, Pantaleão LC, Cimadomo D, Barbosa de Queiroz K, Cheuk CSK, Smith NM, Kay RG, Antrobus R, Hoelle K, Ma MKL, Smith NH, Geyer SH, Reissig LF, Weninger WJ, Siddle K, Willis AE, Lam BYH, Bushell M, Ozanne SE, Constância M. Sandovici I, et al. Among authors: pantaleao lc. Cell Rep. 2024 Sep 24;43(9):114750. doi: 10.1016/j.celrep.2024.114750. Epub 2024 Sep 15. Cell Rep. 2024. PMID: 39283743 Free article.
Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food.
Dearden L, Furigo IC, Pantaleão LC, Wong LWP, Fernandez-Twinn DS, de Almeida-Faria J, Kentistou KA, Carreira MV, Bidault G, Vidal-Puig A, Ong KK, Perry JRB, Donato J Jr, Ozanne SE. Dearden L, et al. Among authors: pantaleao lc. PLoS Biol. 2024 Jun 4;22(6):e3002641. doi: 10.1371/journal.pbio.3002641. eCollection 2024 Jun. PLoS Biol. 2024. PMID: 38833481 Free PMC article.
Programming of cardiac metabolism by miR-15b-5p, a miRNA released in cardiac extracellular vesicles following ischemia-reperfusion injury.
Pantaleão LC, Loche E, Fernandez-Twinn DS, Dearden L, Córdova-Casanova A, Osmond C, Salonen MK, Kajantie E, Niu Y, de Almeida-Faria J, Thackray BD, Mikkola TM, Giussani DA, Murray AJ, Bushell M, Eriksson JG, Ozanne SE. Pantaleão LC, et al. Mol Metab. 2024 Feb;80:101875. doi: 10.1016/j.molmet.2024.101875. Epub 2024 Jan 11. Mol Metab. 2024. PMID: 38218535 Free PMC article.
The metabolic response of human trophoblasts derived from term placentas to metformin.
Tarry-Adkins JL, Robinson IG, Pantaleão LC, Armstrong JL, Thackray BD, Holzner LMW, Knapton AE, Virtue S, Jenkins B, Koulman A, Murray AJ, Ozanne SE, Aiken CE. Tarry-Adkins JL, et al. Among authors: pantaleao lc. Diabetologia. 2023 Dec;66(12):2320-2331. doi: 10.1007/s00125-023-05996-3. Epub 2023 Sep 5. Diabetologia. 2023. PMID: 37670017 Free PMC article.
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Kaisinger LR, Kentistou KA, Stankovic S, Gardner EJ, Day FR, Zhao Y, Mörseburg A, Carnie CJ, Zagnoli-Vieira G, Puddu F, Jackson SP, O'Rahilly S, Farooqi IS, Dearden L, Pantaleão LC, Ozanne SE, Ong KK, Perry JRB. Kaisinger LR, et al. Among authors: pantaleao lc. Cell Genom. 2023 Aug 2;3(8):100362. doi: 10.1016/j.xgen.2023.100362. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601970 Free PMC article.
Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring.
Schoonejans JM, Blackmore HL, Ashmore TJ, Pantaleão LC, Pellegrini Pisani L, Dearden L, Tadross JA, Aiken CE, Fernandez-Twinn DS, Ozanne SE. Schoonejans JM, et al. Among authors: pantaleao lc. Diabetologia. 2022 Dec;65(12):2132-2145. doi: 10.1007/s00125-022-05789-0. Epub 2022 Sep 16. Diabetologia. 2022. PMID: 36112170 Free PMC article.
Effects of maternal diet-induced obesity on metabolic disorders and age-associated miRNA expression in the liver of male mouse offspring.
Mennitti LV, Carpenter AAM, Loche E, Pantaleão LC, Fernandez-Twinn DS, Schoonejans JM, Blackmore HL, Ashmore TJ, Pisani LP, Tadross JA, Hargreaves I, Ozanne SE. Mennitti LV, et al. Among authors: pantaleao lc. Int J Obes (Lond). 2022 Feb;46(2):269-278. doi: 10.1038/s41366-021-00985-1. Epub 2021 Oct 18. Int J Obes (Lond). 2022. PMID: 34663892 Free PMC article.
26 results