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Pivotal Advance: Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes.
Van den Bossche J, Lamers WH, Koehler ES, Geuns JM, Alhonen L, Uimari A, Pirnes-Karhu S, Van Overmeire E, Morias Y, Brys L, Vereecke L, De Baetselier P, Van Ginderachter JA. Van den Bossche J, et al. Among authors: vereecke l. J Leukoc Biol. 2012 May;91(5):685-99. doi: 10.1189/jlb.0911453. Epub 2012 Mar 13. J Leukoc Biol. 2012. PMID: 22416259
Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis.
Lippens S, Lefebvre S, Gilbert B, Sze M, Devos M, Verhelst K, Vereecke L, Mc Guire C, Guérin C, Vandenabeele P, Pasparakis M, Mikkola ML, Beyaert R, Declercq W, van Loo G. Lippens S, et al. Among authors: vereecke l. Cell Death Differ. 2011 Dec;18(12):1845-53. doi: 10.1038/cdd.2011.55. Epub 2011 May 13. Cell Death Differ. 2011. PMID: 21566665 Free PMC article.
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.
Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, Geboes L, Louagie E, Mc Guire C, Vereecke L, Chu Y, Boon L, Staelens S, Matthys P, Lambrecht BN, Schmidt-Supprian M, Pasparakis M, Elewaut D, Beyaert R, van Loo G. Matmati M, et al. Among authors: vereecke l. Nat Genet. 2011 Aug 14;43(9):908-12. doi: 10.1038/ng.874. Nat Genet. 2011. PMID: 21841782
A20 in inflammation and autoimmunity.
Catrysse L, Vereecke L, Beyaert R, van Loo G. Catrysse L, et al. Among authors: vereecke l. Trends Immunol. 2014 Jan;35(1):22-31. doi: 10.1016/j.it.2013.10.005. Epub 2013 Nov 15. Trends Immunol. 2014. PMID: 24246475 Review.
RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.
Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T, Gonçalves A, Sze M, Gilbert B, Kourula S, Goossens V, Lefebvre S, Günther C, Becker C, Bertin J, Gough PJ, Declercq W, van Loo G, Vandenabeele P. Takahashi N, et al. Among authors: vereecke l. Nature. 2014 Sep 4;513(7516):95-9. doi: 10.1038/nature13706. Nature. 2014. PMID: 25186904
52 results