Otzen DE - Search Results

1

Alzheimer's Progenitor Amyloid-β Targets and Dissolves Microbial Amyloids and Impairs Biofilm Function.

Ali SA, Chung KHK, Forgham H, Olsen WP, Kakinen A, Balaji A, Otzen DE, Davis TP, Javed I. Ali SA, et al. Among authors: otzen de. Adv Sci (Weinh). 2023 Oct;10(29):e2301423. doi: 10.1002/advs.202301423. Epub 2023 Aug 18. Adv Sci (Weinh). 2023. PMID: 37594661 Free PMC article.

2

Sequence-targeted Peptides Divert Functional Bacterial Amyloid Towards Destabilized Aggregates and Reduce Biofilm Formation.

Sønderby TV, Louros NN, Khodaparast L, Khodaparast L, Madsen DJ, Olsen WP, Moonen N, Nagaraj M, Sereikaite V, Strømgaard K, Rousseau F, Schymkowitz J, Otzen DE. Sønderby TV, et al. Among authors: otzen de. J Mol Biol. 2023 Jun 1;435(11):168039. doi: 10.1016/j.jmb.2023.168039. Epub 2023 Jun 16. J Mol Biol. 2023. PMID: 37330291 Free article.

3

Mining and engineering activity in catalytic amyloids.

Peña-Díaz S, Ferreira P, Ramos MJ, Otzen DE. Peña-Díaz S, et al. Among authors: otzen de. Methods Enzymol. 2024;697:345-422. doi: 10.1016/bs.mie.2024.03.002. Epub 2024 Apr 20. Methods Enzymol. 2024. PMID: 38816129

4

Young rat microbiota extracts strongly inhibit fibrillation of α-synuclein and protect neuroblastoma cells and zebrafish against α-synuclein toxicity.

Shiraz MG, Nielsen J, Widmann J, Chung KHK, Davis TP, Rasmussen C, Scavenius C, Enghild JJ, Martin-Gallausiaux C, Singh Y, Javed I, Otzen DE. Shiraz MG, et al. Among authors: otzen de. Mol Cells. 2025 Jan;48(1):100161. doi: 10.1016/j.mocell.2024.100161. Epub 2024 Nov 26. Mol Cells. 2025. PMID: 39603509 Free PMC article.

5

Resilience and charge-dependent fibrillation of functional amyloid: Interactions of Pseudomonas biofilm-associated FapB and FapC amyloids.

Golan N, Parizat A, Tabachnikov O, Barnea E, Olsen WP, Otzen DE, Landau M. Golan N, et al. Among authors: otzen de. J Biol Chem. 2024 Dec 18;301(2):108096. doi: 10.1016/j.jbc.2024.108096. Online ahead of print. J Biol Chem. 2024. PMID: 39706277 Free article.

6

Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS.

Adam L, Kumar R, Arroyo-Garcia LE, Molenkamp WH, Nowak JS, Klute H, Farzadfard A, Alkenayeh R, Nielsen J, Biverstål H, Otzen DE, Johansson J, Abelein A. Adam L, et al. Among authors: otzen de. Protein Sci. 2024 Aug;33(8):e5091. doi: 10.1002/pro.5091. Protein Sci. 2024. PMID: 38980078 Free PMC article.

7

Antibodies and α-synuclein: What to target against Parkinson's Disease?

Otzen DE. Otzen DE. Biochim Biophys Acta Proteins Proteom. 2024 Feb 1;1872(2):140943. doi: 10.1016/j.bbapap.2023.140943. Epub 2023 Sep 30. Biochim Biophys Acta Proteins Proteom. 2024. PMID: 37783321 Free article.

8

Extracellular G-quadruplexes and Z-DNA protect biofilms from DNase I, and G-quadruplexes form a DNAzyme with peroxidase activity.

Minero GAS, Møllebjerg A, Thiesen C, Johansen MI, Jørgensen NP, Birkedal V, Otzen DE, Meyer RL. Minero GAS, et al. Among authors: otzen de. Nucleic Acids Res. 2024 Feb 28;52(4):1575-1590. doi: 10.1093/nar/gkae034. Nucleic Acids Res. 2024. PMID: 38296834 Free PMC article.

9

Editorial: Research methods in biochemistry and biophysics.

Otzen DE. Otzen DE. BBA Adv. 2024 Sep 27;6:100121. doi: 10.1016/j.bbadva.2024.100121. eCollection 2024. BBA Adv. 2024. PMID: 39776671 Free PMC article. No abstract available.

10

Structure-Activity Relationship of Fluorinated Benzenesulfonamides as Inhibitors of Amyloid-β Aggregation.

Žvirblis M, Sakalauskas A, Ali Janvand SH, Dudutienė V, Žiaunys M, Sniečkutė R, Otzen DE, Smirnovas V, Matulis D. Žvirblis M, et al. Among authors: otzen de. Chemistry. 2024 Oct 17;30(58):e202402330. doi: 10.1002/chem.202402330. Epub 2024 Sep 24. Chemistry. 2024. PMID: 39109590

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