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CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic.
van Dinther M, Cunningham KT, Singh SP, White MPJ, Campion T, Ciancia C, van Veelen PA, de Ru AH, González-Prieto R, Mukundan A, Byeon CH, Staggers SR, Hinck CS, Hinck AP, Dijke PT, Maizels RM. van Dinther M, et al. Among authors: gonzalez prieto r. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302370120. doi: 10.1073/pnas.2302370120. Epub 2023 Aug 17. Proc Natl Acad Sci U S A. 2023. PMID: 37590410 Free PMC article.
Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis.
Liu S, González-Prieto R, Zhang M, Geurink PP, Kooij R, Iyengar PV, van Dinther M, Bos E, Zhang X, Le Dévédec SE, van de Water B, Koning RI, Zhu HJ, Mesker WE, Vertegaal ACO, Ovaa H, Zhang L, Martens JWM, Ten Dijke P. Liu S, et al. Clin Cancer Res. 2020 Mar 15;26(6):1460-1473. doi: 10.1158/1078-0432.CCR-19-1373. Epub 2019 Dec 19. Clin Cancer Res. 2020. PMID: 31857432 Free PMC article.
SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome.
Salas-Lloret D, Jansen NS, Nagamalleswari E, van der Meulen C, Gracheva E, de Ru AH, Otte HAM, van Veelen PA, Pichler A, Goedhart J, Vertegaal ACO, González-Prieto R. Salas-Lloret D, et al. Among authors: gonzalez prieto r. Sci Adv. 2023 Aug 2;9(31):eadh2073. doi: 10.1126/sciadv.adh2073. Epub 2023 Aug 2. Sci Adv. 2023. PMID: 37531430 Free PMC article.
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.
Salas-Lloret D, García-Rodríguez N, Soto-Hidalgo E, González-Vinceiro L, Espejo-Serrano C, Giebel L, Mateos-Martín ML, de Ru AH, van Veelen PA, Huertas P, Vertegaal ACO, González-Prieto R. Salas-Lloret D, et al. Among authors: gonzalez prieto r. Nat Commun. 2024 May 20;15(1):4292. doi: 10.1038/s41467-024-48427-6. Nat Commun. 2024. PMID: 38769345 Free PMC article.
A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair.
van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. van den Heuvel D, et al. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208860120. doi: 10.1073/pnas.2208860120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893274 Free PMC article.
RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse.
Condezo YB, Sainz-Urruela R, Gomez-H L, Salas-Lloret D, Felipe-Medina N, Bradley R, Wolff ID, Tanis S, Barbero JL, Sánchez-Martín M, de Rooij D, Hendriks IA, Nielsen ML, Gonzalez-Prieto R, Cohen PE, Pendas AM, Llano E. Condezo YB, et al. Among authors: gonzalez prieto r. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2320995121. doi: 10.1073/pnas.2320995121. Epub 2024 Jun 12. Proc Natl Acad Sci U S A. 2024. PMID: 38865271 Free PMC article.
UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.
Yalçin Z, Lam SY, Peuscher MH, van der Torre J, Zhu S, Iyengar PV, Salas-Lloret D, de Krijger I, Moatti N, van der Lugt R, Falcone M, Cerutti A, Bleijerveld OB, Hoekman L, González-Prieto R, Jacobs JJL. Yalçin Z, et al. Among authors: gonzalez prieto r. Nat Commun. 2024 Jun 12;15(1):5032. doi: 10.1038/s41467-024-49431-6. Nat Commun. 2024. PMID: 38866770 Free PMC article.
58 results