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Deep learning integrates histopathology and proteogenomics at a pan-cancer level.
Wang JM, Hong R, Demicco EG, Tan J, Lazcano R, Moreira AL, Li Y, Calinawan A, Razavian N, Schraink T, Gillette MA, Omenn GS, An E, Rodriguez H, Tsirigos A, Ruggles KV, Ding L, Robles AI, Mani DR, Rodland KD, Lazar AJ, Liu W, Fenyö D; Clinical Proteomic Tumor Analysis Consortium. Wang JM, et al. Among authors: tsirigos a. Cell Rep Med. 2023 Sep 19;4(9):101173. doi: 10.1016/j.xcrm.2023.101173. Epub 2023 Aug 14. Cell Rep Med. 2023. PMID: 37582371 Free PMC article.
KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance.
Zavitsanou AM, Pillai R, Hao Y, Wu WL, Bartnicki E, Karakousi T, Rajalingam S, Herrera A, Karatza A, Rashidfarrokhi A, Solis S, Ciampricotti M, Yeaton AH, Ivanova E, Wohlhieter CA, Buus TB, Hayashi M, Karadal-Ferrena B, Pass HI, Poirier JT, Rudin CM, Wong KK, Moreira AL, Khanna KM, Tsirigos A, Papagiannakopoulos T, Koralov SB. Zavitsanou AM, et al. Among authors: tsirigos a. Cell Rep. 2023 Nov 28;42(11):113295. doi: 10.1016/j.celrep.2023.113295. Epub 2023 Oct 26. Cell Rep. 2023. PMID: 37889752 Free PMC article.
Machine learning approaches to predict drug efficacy and toxicity in oncology.
Badwan BA, Liaropoulos G, Kyrodimos E, Skaltsas D, Tsirigos A, Gorgoulis VG. Badwan BA, et al. Among authors: tsirigos a. Cell Rep Methods. 2023 Feb 21;3(2):100413. doi: 10.1016/j.crmeth.2023.100413. eCollection 2023 Feb 27. Cell Rep Methods. 2023. PMID: 36936080 Free PMC article. Review.
MetFinder: A Tool for Automated Quantitation of Metastatic Burden in Histological Sections From Preclinical Models.
Karz A, Coudray N, Bayraktar E, Galbraith K, Jour G, Shadaloey AAS, Eskow N, Rubanov A, Navarro M, Moubarak R, Baptiste G, Levinson G, Mezzano V, Alu M, Loomis C, Lima D, Rubens A, Jilaveanu L, Tsirigos A, Hernando E. Karz A, et al. Among authors: tsirigos a. Pigment Cell Melanoma Res. 2024 Sep 10. doi: 10.1111/pcmr.13195. Online ahead of print. Pigment Cell Melanoma Res. 2024. PMID: 39254030
Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation.
Subudhi I, Konieczny P, Prystupa A, Castillo RL, Sze-Tu E, Xing Y, Rosenblum D, Reznikov I, Sidhu I, Loomis C, Lu CP, Anandasabapathy N, Suárez-Fariñas M, Gudjonsson JE, Tsirigos A, Scher JU, Naik S. Subudhi I, et al. Among authors: tsirigos a. Immunity. 2024 Jul 9;57(7):1665-1680.e7. doi: 10.1016/j.immuni.2024.04.022. Epub 2024 May 20. Immunity. 2024. PMID: 38772365
3D chromatin hubs as regulatory units of identity and survival in human acute leukemia.
Gambi G, Boccalatte F, Rodriguez Hernaez J, Lin Z, Nadorp B, Polyzos A, Tan J, Avrampou K, Inghirami G, Kentsis A, Apostolou E, Aifantis I, Tsirigos A. Gambi G, et al. Among authors: tsirigos a. Mol Cell. 2024 Dec 17:S1097-2765(24)00995-X. doi: 10.1016/j.molcel.2024.11.040. Online ahead of print. Mol Cell. 2024. PMID: 39719705
191 results